Single-cell analyses characterize circulating anti-tumor CD8+ T cells in mice and humans and identify markers for their enrichment

被引：0
|
作者：
Pauken, Kristen E. [1 ,2 ]
Shahid, Osmaan
Lagattuta, Kaitlyn A. [3 ]
Mahuron, Kelly M. [4 ]
Luber, Jacob M. [3 ]
Lowe, Margaret M. [4 ]
Huang, Linglin [2 ]
Delaney, Conor [2 ]
Long, Jaclyn [1 ]
Fung, Megan E. [3 ]
Newcomer, Kathleen [2 ]
Tsai, Katy K. [4 ]
Chow, Melissa [4 ]
Guinn, Samantha [1 ]
Kuchroo, Juhi R. [1 ]
Burke, Kelly P. [3 ]
Schenkel, Jason M. [5 ]
Rosenblum, Michael D. [4 ]
Daud, Adil I. [4 ]
Sharpe, Arlene H. [1 ]
Singer, Meromit [3 ]
机构：
[1] Harvard Med Sch, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Harvard Med Sch, Dana Farber Canc Inst, Boston, MA 02115 USA
[4] Univ Calif San Francisco, San Francisco, CA 94143 USA
[5] Brigham & Womens Hosp, Boston, MA 02115 USA
来源：
JOURNAL OF IMMUNOLOGY | 2021年 / 206卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Interleukin-7 Modulates Anti-Tumor CD8+ T Cell Responses via Its Action on Host Cells
    Deiser, Katrin
    Stoycheva, Diana
    Bank, Ute
    Blankenstein, Thomas
    Schueler, Thomas
    PLOS ONE, 2016, 11 (07):
  • [42] Deciphering the role of CD8+ T cells in IBD: from single-cell analysis to biomarkers
    Katrina Ray
    Nature Reviews Gastroenterology & Hepatology, 2020, 17 : 595 - 595
  • [43] HDAC7 controls CD8+ T cell dependent anti-viral and anti-tumor immunity
    Yerinde, C.
    Keye, J.
    Siegmund, B.
    Glauben, R.
    Weidinger, C.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 16 - 17
  • [44] Neoantigen-mRNA-LNP Vaccine Induces Potent Anti-Tumor CD8+ T cell responses in the tumor
    Nagaoka, Koji
    Tanaka, Hiroki
    Nakanishi, Hideyuki
    Kawamura, Takeshi
    Tanaka, Toshiya
    Yamashita, Takefumi
    Nomura, Sachiyo
    Akita, Hidetaka
    Itaka, Keiji
    Kodama, Tatsuhiko
    Kakimi, Kazuhiro
    CANCER SCIENCE, 2025, 116 : 502 - 502
  • [45] PGE2 over-producing tumor cells prevent activation of anti-tumor specific CD8+ T cell responses
    Ahmadi, M.
    Emery, D.
    Morgan, D.
    IMMUNOLOGY, 2008, 125 : 54 - 55
  • [46] Amphiregulin activates regulatory T lymphocytes and suppresses CD8+ T cell-mediated anti-tumor response in hepatocellular carcinoma cells
    Yuan, Chun-Hui
    Sun, Xiao-Ming
    Zhu, Cheng-Liang
    Liu, Shao-Ping
    Wu, Long
    Chen, Hao
    Feng, Mao-Hui
    Wu, Ke
    Wang, Fu-Bing
    ONCOTARGET, 2015, 6 (31) : 32138 - 32153
  • [47] Single-cell landscape of dynamic changes in CD8+ T cells, CD4+ T cells and exhausted T cells in hepatocellular carcinoma
    Liu, Rongqiang
    Ye, Jing
    Wang, Jianguo
    Ma, Wangbin
    Qiu, Zhendong
    Yu, Jia
    Wang, Weixing
    SCIENTIFIC REPORTS, 2025, 15 (01):
  • [48] Role of CD8+ tissue-resident memory T ( TRM) cells in anti-tumor T-cell response and cancer immunotherapy
    Mami-Chouaib, Fathia
    CANCER RESEARCH, 2018, 78 (13)
  • [49] MEKi in combination with anti-OX40 generates metabolically fit effector CD8+ T cells, enhances stem cell-like memory CD8+ T cells, and leads to strong anti-tumor activity
    Gaur, Pankaj
    Verma, Vivek
    Elayyan, Mays Alreem
    Ramlaoui, Zainab
    Barry, Simon T.
    Valge-Archer, Viia E.
    Smith, Paul D.
    Gupta, Seema
    Khleif, Samir N.
    CANCER RESEARCH, 2022, 82 (12)
  • [50] Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity
    Tejero, Joanne D.
    Hesterberg, Rebecca S.
    Drapela, Stanislav
    Ilter, Didem
    Raizada, Devesh
    Lazure, Felicia
    Kashfi, Hossein
    Liu, Min
    Silvane, Leonardo
    Avram, Dorina
    Fernandez-Garcia, Juan
    Asara, John M.
    Fendt, Sarah-Maria
    Cleveland, John L.
    Gomes, Ana P.
    ONCOGENE, 2025, 44 (02) : 105 - 114
12345