Genetic and Molecular Basis of Inflammasome-mediated Disease

被引:59
作者
Hoffman, Hal M. [1 ]
Brydges, Susannah D. [2 ]
机构
[1] Univ Calif San Diego, Dept Pediat, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Div Rheumatol Allergy & Immunol, La Jolla, CA 92093 USA
关键词
COLD AUTOINFLAMMATORY SYNDROME; ENCODING MEVALONATE KINASE; INNATE IMMUNE ACTIVATION; NLRP3; INFLAMMASOME; NALP3; CUTTING EDGE; ARTICULAR SYNDROME; IL-1-BETA RELEASE; CIAS1; MUTATIONS; CROHNS-DISEASE;
D O I
10.1074/jbc.R110.135491
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:10889 / 10896
页数:8
相关论文
共 91 条
[1]   Inflammasome-dependent Caspase-1 Activation in Cervical Epithelial Cells Stimulates Growth of the Intracellular Pathogen Chlamydia trachomatis [J].
Abdul-Sater, Ali A. ;
Koo, Evonne ;
Haecker, Georg ;
Ojcius, David M. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (39) :26789-26796
[2]   NALP3 forms an IL-lβ-Processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder [J].
Agostini, L ;
Martinon, F ;
Burns, K ;
McDermott, MF ;
Hawkins, PN ;
Tschopp, J .
IMMUNITY, 2004, 20 (03) :319-325
[3]   Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection [J].
Akhter, Anwari ;
Gavrilin, Mikhail A. ;
Frantz, Laura ;
Washington, Songcerae ;
Ditty, Cameron ;
Limoli, Dominique ;
Day, Colby ;
Sarkar, Anasuya ;
Newland, Christie ;
Butchar, Jonathan ;
Marsh, Clay B. ;
Wewers, Mark D. ;
Tridandapani, Susheela ;
Kanneganti, Thirumala-Devi ;
Amer, Amal O. .
PLOS PATHOGENS, 2009, 5 (04)
[4]   De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID) -: A new member of the expanding family of pyrin-associated autoinflammatory diseases [J].
Aksentijevich, I ;
Nowak, M ;
Mallah, M ;
Chae, JJ ;
Watford, WT ;
Hofmann, SR ;
Stein, L ;
Russo, R ;
Goldsmith, D ;
Dent, P ;
Rosenberg, HF ;
Austin, F ;
Remmers, EF ;
Balow, JE ;
Rosenzweig, S ;
Komarow, H ;
Shoham, NG ;
Wood, G ;
Jones, J ;
Mangra, N ;
Carrero, H ;
Adams, BS ;
Moore, TL ;
Schikler, K ;
Hoffman, H ;
Lovell, DJ ;
Lipnick, R ;
Barron, K ;
O'Shea, JJ ;
Kastner, DL ;
Goldbach-Mansky, R .
ARTHRITIS AND RHEUMATISM, 2002, 46 (12) :3340-3348
[5]  
Aksentijevich I, 1997, CELL, V90, P797
[6]   The clinical continuum of cryopyrinopathies -: Novel CIAS1 mutations in north American patients and a new cryopyrin model [J].
Aksentijevich, Ivona ;
Putnam, Christopher D. ;
Remmers, Elaine F. ;
Mueller, James L. ;
Le, Julie ;
Kolodner, Richard D. ;
Moak, Zachary ;
Chuang, Michael ;
Austin, Frances ;
Goldbach-Mansky, Raphaela ;
Hoffman, Hal M. ;
Kastner, Daniel L. .
ARTHRITIS AND RHEUMATISM, 2007, 56 (04) :1273-1285
[7]   The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA [J].
Allen, Irving C. ;
Scull, Margaret A. ;
Moore, Chris B. ;
Holl, Eda K. ;
McElvania-TeKippe, Erin ;
Taxman, Debra J. ;
Guthrie, Elizabeth H. ;
Pickles, Raymond J. ;
Ting, Jenny P. -Y. .
IMMUNITY, 2009, 30 (04) :556-565
[8]   Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors [J].
Babelova, Andrea ;
Moreth, Kristin ;
Tsalastra-Greul, Wasiliki ;
Zeng-Brouwers, Jinyang ;
Eickelberg, Oliver ;
Young, Marian F. ;
Bruckner, Peter ;
Pfeilschifter, Josef ;
Schaefer, Roland M. ;
Groene, Hermann-Josef ;
Schaefer, Liliana .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (36) :24035-24048
[9]  
Bernot A, 1997, NAT GENET, V17, P25
[10]   Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity [J].
Brydges, Susannah D. ;
Mueller, James L. ;
McGeough, Matthew D. ;
Pena, Carla A. ;
Misaghi, Amirhossein ;
Gandhi, Chhavi ;
Putnam, Chris D. ;
Boyle, David L. ;
Firestein, Gary S. ;
Horner, Anthony A. ;
Soroosh, Pejman ;
Watford, Wendy T. ;
O'Shea, John J. ;
Kastner, Daniel L. ;
Hoffman, Hal M. .
IMMUNITY, 2009, 30 (06) :875-887