Silent hypoxia in COVID-19: a gut microbiota connection

被引:8
作者
Gopal, B. Akshita [1 ]
Chakraborty, Soumyadeep [1 ]
Padhan, K. Pratyush [1 ]
Barik, Alok [1 ]
Dixit, Pragyesh [1 ]
Chakraborty, Debashish [1 ]
Poirah, Indrajit [1 ]
Samal, Supriya [1 ]
Sarkar, Arup [2 ]
Bhattacharyya, Asima [1 ]
机构
[1] Natl Inst Sci Educ & Res NISER Bhubaneswar, Sch Biol Sci, HBNI, PO Bhimpur Padanpur, Khurja 752050, Odisha, India
[2] Trident Acad Creat Technol, Bhubaneswar 751024, Odisha, India
来源
CURRENT OPINION IN PHYSIOLOGY | 2021年 / 23卷
关键词
D O I
10.1016/j.cophys.2021.06.010
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has triggered the COVID-19 pandemic. Several factors induce hypoxia in COVID-19. Despite being hypoxic, some SARS-CoV-2-infected individuals do not experience any respiratory distress, a phenomenon termed 'silent (or happy) hypoxia'. Prolonged undetected hypoxia could be dangerous, sometimes leading to death. A few studies attempted to unravel what causes silent hypoxia, however, the exact mechanisms are still elusive. Here, we aim to understand how SARS-CoV-2 causes silent hypoxia.
引用
收藏
页数:8
相关论文
共 65 条
[1]   Computing the Effects of SARS-CoV-2 on Respiration Regulatory Mechanisms in COVID-19 [J].
Baig, Abdul Mannan .
ACS CHEMICAL NEUROSCIENCE, 2020, 11 (16) :2416-2421
[2]   Nondyspnogenic acute hypoxemic respiratory failure in COVID-19 pneumonia [J].
Barreto-Filho, Jose Augusto ;
Seabra-Garcez, Juliane Dantas ;
Garcez, Flavia Barreto ;
Moreira, Thiago S. ;
Drager, Luciano F. .
JOURNAL OF APPLIED PHYSIOLOGY, 2021, 130 (03) :892-897
[3]   Pulmonary manifestations of inflammatory bowel disease: Case presentations and review [J].
Basseri, Benjamin ;
Enayati, Pedram ;
Marchevsky, Alberto ;
Papadakis, Konstantinos A. .
JOURNAL OF CROHNS & COLITIS, 2010, 4 (04) :390-397
[4]   OXIDATIVE STRESS: AN ESSENTIAL FACTOR IN THE PATHOGENESIS OF GASTROINTESTINAL MUCOSAL DISEASES [J].
Bhattacharyya, Asima ;
Chattopadhyay, Ranajoy ;
Mitra, Sankar ;
Crowe, Sheila E. .
PHYSIOLOGICAL REVIEWS, 2014, 94 (02) :329-354
[5]   Unexpectedly High Frequency of Enterococcal Bloodstream Infections in Coronavirus Disease 2019 Patients Admitted to an Italian ICU: An Observational Study [J].
Bonazzetti, Cecilia ;
Morena, Valentina ;
Giacomelli, Andrea ;
Oreni, Letizia ;
Casalini, Giacomo ;
Galimberti, Laura Rina ;
Bolis, Matteo ;
Rimoldi, Matteo ;
Ballone, Elisabetta ;
Colombo, Riccardo ;
Ridolfo, Anna Lisa ;
Antinori, Spinello .
CRITICAL CARE MEDICINE, 2021, 49 (01) :E31-E40
[6]   The gut microbiota influences blood-brain barrier permeability in mice [J].
Braniste, Viorica ;
Al-Asmakh, Maha ;
Kowal, Czeslawa ;
Anuar, Farhana ;
Abbaspour, Afrouz ;
Toth, Miklos ;
Korecka, Agata ;
Bakocevic, Nadja ;
Ng, Lai Guan ;
Kundu, Parag ;
Gulyas, Balazs ;
Halldin, Christer ;
Hultenby, Kjell ;
Nilsson, Harriet ;
Hebert, Hans ;
Volpe, Bruce T. ;
Diamond, Betty ;
Pettersson, Sven .
SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (263)
[7]   Asymptomatic hypoxia in COVID-19 is associated with poor outcome [J].
Brouqui, Philippe ;
Amrane, Sophie ;
Million, Matthieu ;
Cortaredona, Sebastien ;
Parola, Philippe ;
Lagier, Jean-Christophe ;
Raoult, Didier .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2021, 102 :233-238
[8]   Small talk: microbial metabolites involved in the signaling from microbiota to brain [J].
Caspani, Giorgia ;
Swann, Jonathan .
CURRENT OPINION IN PHARMACOLOGY, 2019, 48 :99-106
[9]   Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2 [J].
Catanzaro, Michele ;
Fagiani, Francesca ;
Racchi, Marco ;
Corsini, Emanuela ;
Govoni, Stefano ;
Lanni, Cristina .
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 5 (01)
[10]   The microbial coinfection in COVID-19 [J].
Chen, Xi ;
Liao, Binyou ;
Cheng, Lei ;
Peng, Xian ;
Xu, Xin ;
Li, Yuqing ;
Hu, Tao ;
Li, Jiyao ;
Zhou, Xuedong ;
Ren, Biao .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2020, 104 (18) :7777-7785