Vitamin B12 Deficiency Anemia and Polyneuropathy Due to Chronic Radiation Enteritis

被引:4
|
作者
Fukuda, Hiroyuki [1 ]
Takekuma, Munetaka [2 ]
Hirashima, Yasuyuki [2 ]
机构
[1] Shizuoka Canc Ctr, Div Neurol, Shizuoka, Japan
[2] Shizuoka Canc Ctr, Div Gynecol, Shizuoka, Japan
关键词
gynecological cancer; megaloblastic anemia; polyneuropathy; radiation enteritis; vitamin B12 deficiency; MALABSORPTION;
D O I
10.2169/internalmedicine.3695-19
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 62-year-old Japanese woman developed numbness of the extremities and megaloblastic anemia. She had undergone total abdominal hysterectomy, whole-pelvis radiation therapy and chemotherapy for gynecological cancer 10 years before. Chronic abdominal pain, diarrhea and intermittent small-bowel obstruction had afflicted her for a long time. We diagnosed her with vitamin B12 deficiency anemia and polyneuropathy due to chronic radiation enteritis causing malabsorption. Vitamin B12 injections improved her numbness and anemia. The early diagnosis and treatment of deficiency of vitamin B12 are important. Physicians should regularly measure vitamin B12 levels and supplement vitamin B12 as needed in patients with chronic radiation enteritis.
引用
收藏
页码:859 / 861
页数:3
相关论文
共 50 条
  • [1] Megaloblastic anemia in children caused by vitamin B12 deficiency
    Rössler, J
    Breitenstein, S
    Havers, W
    MONATSSCHRIFT KINDERHEILKUNDE, 2001, 149 (05) : 497 - 503
  • [2] Clinical relevance of testing for metabolic vitamin B12 deficiency in patients with polyneuropathy
    Warendorf, Janna K.
    van Doormaal, Perry T. C.
    Vrancken, Alexander F. J. E.
    Verhoeven-Duif, Nanda M.
    van Eijk, Ruben P. A.
    van den Berg, Leonard H.
    Notermans, Nicolette C.
    NUTRITIONAL NEUROSCIENCE, 2022, 25 (12) : 2536 - 2546
  • [3] Vitamin B12 deficiency in an infant child of a mother with pernicious anemia
    Dapueto, Gabriel
    Vomero, Alejandra
    Garcia, Loreley
    ANDES PEDIATRICA, 2022, 93 (03): : 410 - 415
  • [4] Severe neuropsychiatric symptoms due to vitamin b12 deficiency: a case of pernicious anemia or metformin use?
    Urbano, Joana
    Fernandes, Ana Catarina
    Ferreira, Pestana
    Pimenta, Joana
    GALICIA CLINICA, 2015, 76 (04): : 178 - 180
  • [5] Serial nerve conduction studies in vitamin B12 deficiency-associated polyneuropathy
    Huang, Chi-Ren
    Chang, Wen-Neng
    Tsai, Nai-Wen
    Lu, Cheng-Hsien
    NEUROLOGICAL SCIENCES, 2011, 32 (01) : 183 - 186
  • [6] Serial nerve conduction studies in vitamin B12 deficiency-associated polyneuropathy
    Chi-Ren Huang
    Wen-Neng Chang
    Nai-Wen Tsai
    Cheng-Hsien Lu
    Neurological Sciences, 2011, 32 : 183 - 186
  • [7] Vitamin B12 Deficiency Megaloblastic Anemia in a Patient with Acquired Immunodeficiency Syndrome
    Kim, Bongyoung
    Kim, Jieun
    Hwang, Soonwoo
    Lee, Yuhwa
    Park, Junghwan
    Moon, Shinje
    Choi, Jiyoung
    Song, June-Seok
    Jeong, Jongheon
    Pai, Hyunjoo
    INFECTION AND CHEMOTHERAPY, 2011, 43 (03): : 266 - 269
  • [8] Efficacy of oral methylcobalamin in treatment of vitamin B12 deficiency anemia in children
    Verma, Deepti
    Chandra, Jagdish
    Kumar, Praveen
    Shukla, Shailaja
    Sengupta, Shantanu
    PEDIATRIC BLOOD & CANCER, 2017, 64 (12)
  • [9] STUDY TO KNOW THE VITAMIN B12 DEFICIENCY IN PATIENTS HAVING MEGALOBLASTIC ANEMIA
    Qadir, Aaisha
    Khan, Sidra
    Hasan, Muhammad Usman
    INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 6 (04): : 8024 - 8028
  • [10] Severe Vitamin B12 Deficiency Presenting as Pancytopenia, Hemolytic Anemia, and Paresthesia: Could Your B12 Be Any Lower?
    Pelling, Mary M.
    Kimura, Stephen T.
    Han, Erica J.
    Shin, Yoo Mee
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (09)