Hepatitis B virus reactivation after effective sofosbuvir and ribavirin treatment in a patient with occult hepatitis B virus infection

被引：0
|
作者：
Odolini, Silvia [1 ,2 ]
Lanza, Paola [1 ,2 ]
Spinetti, Angiola [1 ,2 ]
Zaltron, Serena [1 ,2 ]
Urbinati, Lucia [1 ,2 ]
Vavassori, Andrea [1 ,2 ]
Nasta, Paola [1 ,2 ]
Festa, Elena [1 ,2 ]
Gargiulo, Franco [3 ]
Rodella, Anna [3 ]
Caruso, Arnaldo [3 ]
Casari, Salvatore [1 ,2 ]
Castelli, Francesco [1 ,2 ]
Vigano, Mauro [4 ]
机构：
[1] Univ Brescia, Clin Infect & Trop Dis, Brescia, Italy
[2] Spedali Civil Brescia, Gen Hosp, Brescia, Italy
[3] Brescia Spedali Civili, Lab Microbiol, Gen Hosp, Brescia, Italy
[4] Univ Milan, Hepatol Unit, Osped San Giuseppe, Milan, Italy
来源：
NEW MICROBIOLOGICA | 2017年 / 40卷 / 03期
关键词：
Reactivation; DAAs; HCV; Occult B hepatitis; C-VIRUS; COINFECTION; THERAPY;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Reactivation of the hepatitis B virus (HBV) has been reported in patients with occult infection (OBI), i. e. HBV surface antigen (HBsAg) negative, HBV core antibody (anti-HBc) positive +/- antibodies against HBsAg (anti-HBs) and detectable HBV DNA in serum or liver, receiving immunosuppressive or cytotoxic therapies. Recently, concerns have been raised regarding the risk of HBV reactivation in OBI patients treated with direct acting antiviral agents (DAAs) for chronic hepatitis C (CHC). Here we describe a case of HBV reactivation in a 72-year-old woman with OBI as a possible consequence of effective treatment with sofosbuvir (SOF) and ribavirin (Rbv) for genotype 2a/2c CHC.
引用
收藏
页码：218 / 220
页数：3
相关论文
共 50 条
  • [41] Risk of viral reactivation in patients with occult hepatitis B virus infection during ruxolitinib treatment
    Harinder Gill
    Garret M. K. Leung
    Wai-Kay Seto
    Yok-Lam Kwong
    Annals of Hematology, 2019, 98 : 215 - 218
  • [42] An overview of occult hepatitis B virus infection
    Said, Zeinab Nabil Ahmed
    WORLD JOURNAL OF GASTROENTEROLOGY, 2011, 17 (15) : 1927 - 1938
  • [43] Control of occult hepatitis B virus infection
    Garces, Marta Lalana
    Pastor, Oihana Ortiz
    Enrech, Gemma Sole
    Guerra-Ruiz, Armando R. R.
    Mercadal, Gregori Casals
    Lafuente, Alejandro Almeria
    Vizoso, Maria Antonieta Ballesteros
    Medina, Pablo Gabriel
    Fernandez, Sergio Salgueero
    Trillo, Angielys Zamora
    de la Serna, Isabel Aured
    Hurtado, Juan Carlos
    Perez-Del-Pulgar, Sofia
    Forns, Xavier
    Ruiz, Manuel Morales
    ADVANCES IN LABORATORY MEDICINE-AVANCES EN MEDICINA DE LABORATORIO, 2022, 3 (04): : 321 - 330
  • [44] Risk of viral reactivation in patients with occult hepatitis B virus infection during ruxolitinib treatment
    Gill, Harinder
    Leung, Garret M. K.
    Seto, Wai-Kay
    Kwong, Yok-Lam
    ANNALS OF HEMATOLOGY, 2019, 98 (01) : 215 - 218
  • [45] Hepatitis B virus reactivation sustained by a hepatitis B virus surface antigen immune-escape mutant isolate in a patient who was hepatitis B core antibody positive during treatment with sofosbuvir and velpatasvir for hepatitis C virus infection: a case report
    Luca Foroghi Biland
    Ludovica Ferrari
    Vincenzo Malagnino
    Elisabetta Teti
    Carlotta Cerva
    Adele Gentile
    Marianna Aragri
    Romina Salpini
    Valentina Svicher
    Massimo Andreoni
    Loredana Sarmati
    Journal of Medical Case Reports, 13
  • [46] Hepatitis B virus reactivation sustained by a hepatitis B virus surface antigen immune-escape mutant isolate in a patient who was hepatitis B core antibody positive during treatment with sofosbuvir and velpatasvir for hepatitis C virus infection: a case report
    Biland, Luca Foroghi
    Ferrari, Ludovica
    Malagnino, Vincenzo
    Teti, Elisabetta
    Cerva, Carlotta
    Gentile, Adele
    Aragri, Marianna
    Salpini, Romina
    Svicher, Valentina
    Andreoni, Massimo
    Sarmati, Loredana
    JOURNAL OF MEDICAL CASE REPORTS, 2019, 13 (01)
  • [47] Distribution of hepatitis B virus in the liver of chronic hepatitis C patients with occult hepatitis B virus infection
    Rodríguez-Iñigo, E
    Mariscal, L
    Bartolomé, J
    Castillo, I
    Navacerrada, C
    Ortiz-Movilla, N
    Pardo, M
    Carreño, V
    JOURNAL OF MEDICAL VIROLOGY, 2003, 70 (04) : 571 - 580
  • [48] Occult hepatitis B virus infection with positive hepatitis B e antigen
    Han, Zhenge
    Liu, Yong
    Pan, Jinshun
    Bi, Yongchun
    Liu, Jingli
    Zhou, Yi-Hua
    CLINICA CHIMICA ACTA, 2015, 438 : 266 - 268
  • [49] Occult hepatitis B virus infection in hepatitis B vaccinated children in Taiwan
    Mu, Shu-Chi
    Lin, Yu-Min
    Jow, Guey-Mel
    Chen, Bing-Fang
    JOURNAL OF HEPATOLOGY, 2009, 50 (02) : 264 - 272
  • [50] Occult hepatitis B virus infection among people with a family history of chronic hepatitis B virus infection
    Zhang, Zhenhua
    Zhang, Ling
    Dai, Yu
    Jin, Lei
    Sun, Binghu
    Su, Qian
    Li, Xu
    JOURNAL OF MEDICAL VIROLOGY, 2015, 87 (11) : 1890 - 1898
12345