Hepatitis B virus reactivation after effective sofosbuvir and ribavirin treatment in a patient with occult hepatitis B virus infection

被引：0
|
作者：
Odolini, Silvia [1 ,2 ]
Lanza, Paola [1 ,2 ]
Spinetti, Angiola [1 ,2 ]
Zaltron, Serena [1 ,2 ]
Urbinati, Lucia [1 ,2 ]
Vavassori, Andrea [1 ,2 ]
Nasta, Paola [1 ,2 ]
Festa, Elena [1 ,2 ]
Gargiulo, Franco [3 ]
Rodella, Anna [3 ]
Caruso, Arnaldo [3 ]
Casari, Salvatore [1 ,2 ]
Castelli, Francesco [1 ,2 ]
Vigano, Mauro [4 ]
机构：
[1] Univ Brescia, Clin Infect & Trop Dis, Brescia, Italy
[2] Spedali Civil Brescia, Gen Hosp, Brescia, Italy
[3] Brescia Spedali Civili, Lab Microbiol, Gen Hosp, Brescia, Italy
[4] Univ Milan, Hepatol Unit, Osped San Giuseppe, Milan, Italy
来源：
NEW MICROBIOLOGICA | 2017年 / 40卷 / 03期
关键词：
Reactivation; DAAs; HCV; Occult B hepatitis; C-VIRUS; COINFECTION; THERAPY;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Reactivation of the hepatitis B virus (HBV) has been reported in patients with occult infection (OBI), i. e. HBV surface antigen (HBsAg) negative, HBV core antibody (anti-HBc) positive +/- antibodies against HBsAg (anti-HBs) and detectable HBV DNA in serum or liver, receiving immunosuppressive or cytotoxic therapies. Recently, concerns have been raised regarding the risk of HBV reactivation in OBI patients treated with direct acting antiviral agents (DAAs) for chronic hepatitis C (CHC). Here we describe a case of HBV reactivation in a 72-year-old woman with OBI as a possible consequence of effective treatment with sofosbuvir (SOF) and ribavirin (Rbv) for genotype 2a/2c CHC.
引用
收藏
页码：218 / 220
页数：3
相关论文
共 50 条
  • [21] Hepatitis D virus infection in patients with hepatitis B virus occult infection
    Oubina, Jose R.
    Delfino, Cecilia M.
    Mathet, Veronica L.
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2019, 31 (05) : 646 - 646
  • [22] Hepatitis B virus reactivation after ibrutinib treatment
    Alventosa Mateu, Carlos
    Urquijo Ponce, Juan Jose
    Mena Duran, Armando
    Latorre Sanchez, Mercedes
    Castello Miralles, Inmaculada
    Linares Garcia, Mariano
    Diago, Moises
    REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS, 2024, 116 (01) : 43 - 43
  • [23] Hepatitis B virus reactivation after ustekinumab treatment
    Purnak, S.
    Purnak, T.
    BRITISH JOURNAL OF DERMATOLOGY, 2014, 170 (02) : 477 - 478
  • [24] Reactivation of hepatitis B virus infection following ruxolitinib treatment in a patient with myelofibrosis
    Caocci, G.
    Murgia, F.
    Podda, L.
    Solinas, A.
    Atzeni, S.
    La Nasa, G.
    LEUKEMIA, 2014, 28 (01) : 225 - 227
  • [25] Reactivation of hepatitis B virus infection following ruxolitinib treatment in a patient with myelofibrosis
    G Caocci
    F Murgia
    L Podda
    A Solinas
    S Atzeni
    G La Nasa
    Leukemia, 2014, 28 : 225 - 227
  • [26] No Evidence of Reactivation of Hepatitis B Virus Among Patients Treated With Ledipasvir-Sofosbuvir for Hepatitis C Virus Infection
    Sulkowski, Mark S.
    Chuang, Wan-Long
    Kao, Jia-Horng
    Yang, Jenny C.
    Gao, Bing
    Brainard, Diana M.
    Han, Kwang-Hyub
    Gane, Edward
    CLINICAL INFECTIOUS DISEASES, 2016, 63 (09) : 1202 - 1204
  • [27] Risk of Hepatitis B Virus Reactivation Among Patients Treated With Ledipasvir-Sofosbuvir for Hepatitis C Virus Infection
    Yanny, Beshoy T.
    Latt, Nyan L.
    Saab, Sammy
    Han, Steven
    Choi, Gina
    Kramer, Jason
    Sahota, Amandeep K.
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 2018, 52 (10) : 908 - 912
  • [28] Reactivation of Hepatitis B Virus Following Treatment of Hepatitis C Virus Infection in Coinfected Patients
    Ozaras, Resat
    Balkan, Ilker Inanc
    Yemisen, Mucahit
    Mete, Bilgul
    Tabak, Fehmi
    CLINICAL INFECTIOUS DISEASES, 2017, 64 (10) : 1461 - 1462
  • [29] Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection
    Sasaki, Tokio
    Kakisaka, Keisuke
    Miyasaka, Akio
    Nishiya, Masao
    Yanagawa, Naoki
    Kuroda, Hidekatsu
    Matsumoto, Takayuki
    Takahashi, Masaharu
    Okamoto, Hiroaki
    CLINICAL JOURNAL OF GASTROENTEROLOGY, 2024, 17 (04) : 683 - 690
  • [30] Prevalence of occult hepatitis B virus infection
    Maria Luisa Gutiérrez-García
    Conrado M Fernandez-Rodriguez
    Jose Luis Lledo-Navarro
    Ingrid Buhigas-Garcia
    World Journal of Gastroenterology, 2011, 17 (12) : 1538 - 1542
12345