90Sr THERAPY FOR ORAL SQUAMOUS CELL CARCINOMA IN TWO CATS

被引:4
作者
Nagata, Koichi [1 ]
Selting, Kimberly A. [1 ]
Cook, Cristi R. [1 ]
Renschler, Metta [1 ]
Lattimer, Jimmy C. [1 ]
机构
[1] Univ Missouri, Dept Vet Med, Columbia, MO 65211 USA
关键词
cats; oral squamous cell carcinoma; strontium; CLONAL EVOLUTION; P53; MUTATION; NASAL PLANUM; EXPRESSION; NEOPLASIA; CARCINOGENESIS; PLESIOTHERAPY; EXPOSURE; BLADDER; CANCERS;
D O I
10.1111/j.1740-8261.2010.01731.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Two cats with a superficial oral squamous cell carcinoma responded favorably to treatment using a 90Sr probe. From one to six fields were applied per tumor, depending on tumor size. The surface dose per treatment ranged from 75 to 150 Gy and the total surface dose ranged from 200 to 500 Gy. Adverse effects were minimal. The cats survived 7 months and 5 years 9 months from the time of diagnosis. These data indicate that with careful patient selection 90Sr may be useful for the treatment of feline oral squamous cell carcinoma in some patients.
引用
收藏
页码:114 / 117
页数:4
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