90Sr THERAPY FOR ORAL SQUAMOUS CELL CARCINOMA IN TWO CATS

被引:4
作者
Nagata, Koichi [1 ]
Selting, Kimberly A. [1 ]
Cook, Cristi R. [1 ]
Renschler, Metta [1 ]
Lattimer, Jimmy C. [1 ]
机构
[1] Univ Missouri, Dept Vet Med, Columbia, MO 65211 USA
关键词
cats; oral squamous cell carcinoma; strontium; CLONAL EVOLUTION; P53; MUTATION; NASAL PLANUM; EXPRESSION; NEOPLASIA; CARCINOGENESIS; PLESIOTHERAPY; EXPOSURE; BLADDER; CANCERS;
D O I
10.1111/j.1740-8261.2010.01731.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Two cats with a superficial oral squamous cell carcinoma responded favorably to treatment using a 90Sr probe. From one to six fields were applied per tumor, depending on tumor size. The surface dose per treatment ranged from 75 to 150 Gy and the total surface dose ranged from 200 to 500 Gy. Adverse effects were minimal. The cats survived 7 months and 5 years 9 months from the time of diagnosis. These data indicate that with careful patient selection 90Sr may be useful for the treatment of feline oral squamous cell carcinoma in some patients.
引用
收藏
页码:114 / 117
页数:4
相关论文
共 38 条
[1]  
Borczuk Alain C, 2007, Proc Am Thorac Soc, V4, P127, DOI 10.1513/pats.200607-143JG
[2]  
BOSTOCK DE, 1972, J SMALL ANIM PRACT, V3, P119
[3]   Response of feline oral squamous cell carcinoma to palliative radiation therapy [J].
Bregazzi, VS ;
LaRue, SP ;
Powers, BE ;
Fettman, MJ ;
Ogilvie, GK ;
Withrow, SJ .
VETERINARY RADIOLOGY & ULTRASOUND, 2001, 42 (01) :77-79
[4]  
Chu TY, 1999, GENE CHROMOSOME CANC, V24, P127, DOI 10.1002/(SICI)1098-2264(199902)24:2<127::AID-GCC5>3.0.CO
[5]  
2-8
[6]  
COPPER MP, 1993, CANCER, V71, P825, DOI 10.1002/1097-0142(19930201)71:3<825::AID-CNCR2820710327>3.0.CO
[7]  
2-X
[8]  
Dhaliwal RS, 1998, COMP CONT EDUC PRACT, V20, P1011
[9]   Multiple limbal haemangiosarcomas in a border collie dog: management by lamellar keratectomy/sclerectomy and strontium-90 beta plesiotherapy [J].
Donaldson, D. ;
Sansom, J. ;
Murphy, S. ;
Scase, T. .
JOURNAL OF SMALL ANIMAL PRACTICE, 2006, 47 (09) :545-549
[10]   Canine limbal melanoma: 30 cases (1992-2004). Part 1. Signalment, clinical and histological features and pedigree analysis [J].
Donaldson, D ;
Sansom, J ;
Scase, T ;
Adams, V ;
Mellersh, C .
VETERINARY OPHTHALMOLOGY, 2006, 9 (02) :115-119