Monte-Carlo Simulation of Multiple-Molecular-Motor Transport

被引:3
作者
Wang Zi-Qing [1 ]
Wang Guo-Dong [1 ]
Shen Wei-Bo [1 ]
机构
[1] NW A&F Univ, Coll Sci, Yangling 712100, Peoples R China
关键词
multimotor transport; velocity; stall force; run-length; TUG-OF-WAR; CARGO TRANSPORT; CYTOPLASMIC DYNEIN; KINESIN MOLECULES; MOVEMENT; MODEL; DESCRIBES; BEHAVIOR; NUMBER; CYCLE;
D O I
10.1088/0253-6102/54/4/34
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Multimotor transport is studied by Monte-Carlo simulation with consideration of motor detachment from the filament. Our work shows, in the case of low load, the velocity of multi-motor system can decrease or increase with increasing motor numbers depending on the single motor force-velocity curve. The stall force and run-length reduced greatly compared to other models. Especially in the case of low ATP concentrations, the stall force of multi motor transport even smaller than the single motor's stall force.
引用
收藏
页码:768 / 772
页数:5
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