Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation

被引:114
|
作者
Arce-Sillas, Asiel [1 ]
Denisse Alvarez-Luquin, Diana [1 ]
Tamaya-Dominguez, Beatriz [1 ]
Gomez-Fuentes, Sandra [1 ]
Trejo-Garcia, Abel [1 ]
Melo-Salas, Marlene [1 ]
Cardenas, Graciela [1 ]
Rodriguez-Ramirez, Juan [1 ]
Adalid-Peralta, Laura [1 ,2 ]
机构
[1] Inst Nacl Neurol & Neurocirug, Mexico City 14269, DF, Mexico
[2] Inst Nacl Neurol & Neurocirug, Inst Invest Biomed, Unidad Perifer, Mexico City 14269, DF, Mexico
关键词
GRANZYME-B; DENDRITIC CELLS; MEDIATED SUPPRESSION; INDOLEAMINE 2,3-DIOXYGENASE; TARGET-CELLS; CUTTING EDGE; C-MAF; EXPRESSION; IL-10; INTERLEUKIN-10;
D O I
10.1155/2016/1720827
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
T regulatory cells play a key role in the control of the immune response, both in health and during illness. While the mechanisms through which T regulatory cells exert their function have been extensively described, their molecular effects on effector cells have received little attention. Thus, this revision is aimed at summarizing our current knowledge on those regulation mechanisms on the target cells from a molecular perspective.
引用
收藏
页数:12
相关论文
共 50 条
  • [31] Differentiation and function of Foxp3+ effector regulatory T cells
    Cretney, Erika
    Kallies, Axel
    Nutt, Stephen L.
    TRENDS IN IMMUNOLOGY, 2013, 34 (02) : 74 - 80
  • [32] Osteopontin and Regulatory T Cells in Effector Phase of Allergic Contact Dermatitis
    Reduta, Teresa
    Bacharewicz-Szczerbicka, Joanna
    Stasiak-Barmuta, Anna
    Kaminski, Tomasz W. W.
    Flisiak, Iwona
    JOURNAL OF CLINICAL MEDICINE, 2023, 12 (04)
  • [33] Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity
    Chen, Xin
    Oppenheim, Joost J.
    FEBS LETTERS, 2011, 585 (23) : 3611 - 3618
  • [34] Lineage Reprogramming of Effector Regulatory T Cells in Cancer
    Dixon, Michael L.
    Leavenworth, Jonathan D.
    Leavenworth, Jianmei W.
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [35] Trafficking of regulatory T cells in the intestinal immune system
    Pabst, Oliver
    INTERNATIONAL IMMUNOLOGY, 2013, 25 (03) : 139 - 143
  • [36] Regulatory T cells: Master thieves of the immune system
    Akkaya, Billur
    Shevach, Ethan M.
    CELLULAR IMMUNOLOGY, 2020, 355
  • [37] Lineage Tracking the Generation of T Regulatory Cells From Microbial Activated T Effector Cells in Naive Mice
    Zhu, Kun
    He, Chenfeng
    Liu, Si-Qi
    Qu, Mingjuan
    Xie, Tao
    Yang, Xiaofeng
    Lei, Lei
    Zhou, Xiaobo
    Shi, Lin
    Zhang, Dan
    Cheng, Yanbin
    Sun, Yae
    Zheng, Huiqiang
    Shen, Xiaonan
    Li, Qijing
    Jiang, Ning
    Zhang, Baojun
    FRONTIERS IN IMMUNOLOGY, 2020, 10
  • [38] Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
    Rosana Domingues
    Gabriel Costa de Carvalho
    Valéria Aoki
    Alberto José da Silva Duarte
    Maria Notomi Sato
    Journal of Translational Medicine, 14
  • [39] MicroRNAs and immune regulatory T cells
    Zhou, Li
    Seo, Kook Heon
    Wong, Henry K.
    Mi, Qing-Sheng
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2009, 9 (05) : 524 - 527
  • [40] Natural and induced T regulatory cells in cancer
    Adeegbe, Dennis O.
    Nishikawa, Hiroyoshi
    FRONTIERS IN IMMUNOLOGY, 2013, 4