Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation

被引:119
作者
Arce-Sillas, Asiel [1 ]
Denisse Alvarez-Luquin, Diana [1 ]
Tamaya-Dominguez, Beatriz [1 ]
Gomez-Fuentes, Sandra [1 ]
Trejo-Garcia, Abel [1 ]
Melo-Salas, Marlene [1 ]
Cardenas, Graciela [1 ]
Rodriguez-Ramirez, Juan [1 ]
Adalid-Peralta, Laura [1 ,2 ]
机构
[1] Inst Nacl Neurol & Neurocirug, Mexico City 14269, DF, Mexico
[2] Inst Nacl Neurol & Neurocirug, Inst Invest Biomed, Unidad Perifer, Mexico City 14269, DF, Mexico
关键词
GRANZYME-B; DENDRITIC CELLS; MEDIATED SUPPRESSION; INDOLEAMINE 2,3-DIOXYGENASE; TARGET-CELLS; CUTTING EDGE; C-MAF; EXPRESSION; IL-10; INTERLEUKIN-10;
D O I
10.1155/2016/1720827
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
T regulatory cells play a key role in the control of the immune response, both in health and during illness. While the mechanisms through which T regulatory cells exert their function have been extensively described, their molecular effects on effector cells have received little attention. Thus, this revision is aimed at summarizing our current knowledge on those regulation mechanisms on the target cells from a molecular perspective.
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页数:12
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