G-protein coupled receptors: Models, mutagenesis, and drug design

被引：115
作者：
Bikker, JA
Trumpp-Kallmeyer, S
Humblet, C
机构：
[1] Warner Lambert Parke Davis, Parke Davis Pharmaceut Res Div, Biomol Struct & Drug Design, Ann Arbor, MI 48105 USA
[2] Parke Davis Neurosci Res Ctr, Cambridge CB2 2QB, England
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1998年 / 41卷 / 16期
关键词：
D O I：
10.1021/jm970767a
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：2911 / 2927
页数：17
相关论文
共 153 条
[1]  
[Anonymous], 1994, The G-Protein linked Receptor Fact Book
[2]   MOLECULAR DETERMINANTS OF HUMAN RED/GREEN COLOR DISCRIMINATION [J].
ASENJO, AB ;
RIM, J ;
OPRIAN, DD .
NEURON, 1994, 12 (05) :1131-1138
[3]   An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors [J].
Baldwin, JM ;
Schertler, GFX ;
Unger, VM .
JOURNAL OF MOLECULAR BIOLOGY, 1997, 272 (01) :144-164
[4]   THE PROBABLE ARRANGEMENT OF THE HELICES IN G-PROTEIN-COUPLED RECEPTORS [J].
BALDWIN, JM .
EMBO JOURNAL, 1993, 12 (04) :1693-1703
[5]  
Ballesteros JA., 1995, METH NEUROSCI, V25, P366, DOI DOI 10.1016/S1043-9471(05)80049-7
[6]   THE CONSERVED 7-TRANSMEMBRANE SEQUENCE NP(X)(2,3)Y OF THE G-PROTEIN-COUPLED RECEPTOR SUPERFAMILY REGULATES MULTIPLE PROPERTIES OF THE BETA(2)-ADRENERGIC RECEPTOR [J].
BARAK, LS ;
MENARD, L ;
FERGUSON, SSG ;
COLAPIETRO, AM ;
CARON, MG .
BIOCHEMISTRY, 1995, 34 (47) :15407-15414
[7]   How photons start vision [J].
Baylor, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (02) :560-565
[8]   Structural characterization and binding sites of G-protein-coupled receptors [J].
BeckSickinger, AG .
DRUG DISCOVERY TODAY, 1996, 1 (12) :502-513
[9]  
Bikker JA, 1996, ALFRED BENZON SYMP S, V39, P375
[10]   2-PHOTON SPECTROSCOPY OF LOCKED-11-CIS-RHODOPSIN - EVIDENCE FOR A PROTONATED SCHIFF-BASE IN A NEUTRAL PROTEIN-BINDING SITE [J].
BIRGE, RR ;
MURRAY, LP ;
PIERCE, BM ;
AKITA, H ;
BALOGHNAIR, V ;
FINDSEN, LA ;
NAKANISHI, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (12) :4117-4121
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