Wound dressing from polyvinyl alcohol/chitosan electrospun fiber membrane loaded with OH-CATH30 nanoparticles

被引：125
作者：
Zou, Pengfei [1 ]
Lee, Wen-Hui [2 ,3 ]
Gao, Zhiqin [3 ]
Qin, Di [3 ]
Wang, Yuxia [1 ]
Liu, Jiao [1 ]
Sun, Tongyi [3 ]
Gao, Yuanyuan [1 ]
机构：
[1] Weifang Med Univ, Sch Pharm, Baotong Rd, Weifang 261053, Shandong, Peoples R China
[2] Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Key Lab Bioact Peptide Yunnan Prov, Kunming 650223, Yunnan, Peoples R China
[3] Weifang Med Univ, Sch Biosci & Technol, Key Lab Biol Med Univ Shandong Prov, Baotong Rd, Weifang 261053, Shandong, Peoples R China
来源：
CARBOHYDRATE POLYMERS | 2020年 / 232卷 / 232期
基金：
中国国家自然科学基金;
关键词：
OH-CATH30; PVA; Wound healing; Nanofibers; Nanoparticles; ANTIMICROBIAL PEPTIDE OH-CATH30; IN-VITRO; NANOFIBROUS MEMBRANE; SILVER NANOPARTICLES; EFFICIENT STRATEGY; ANTIBACTERIAL; DRUG; ALGINATE; MATS; FABRICATION;
D O I：
10.1016/j.carbpol.2019.115786
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Novel nanomaterials have been developed for antimicrobial and wound healing applications. Here, we report the preparation of a polyvinyl alcohol/chitosan (PVA/CS) nanofiber with carboxymethyl chitosan nanoparticles (CMCS-OH30 NPs) encapsulating the antibacterial peptide OH-CATH30 (OH-30). The PVA/CS nanofibers containing OH-30 NPs (NP-30-NFs) obtained via electrospinning could achieve a secondary embedded OH-30. The effect of NP-30-NFs on the release of OH-30 was investigated through high-performance liquid chromatography. The antibacterial activities of NP-30-NFs against Escherichia coli and Staphylococcus aureus were studied by bacterial plate counting. NP-30-NFs containing different concentrations of NPs were applied to mouse skin wounds to determine their effectiveness in promoting wound healing. Results showed that NP-30-NFs exhibited antibacterial properties and promoted skin wound healing.
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页数：10
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共 48 条
[41]   Erythropoietin/aloe vera-releasing wet-electrospun polyvinyl alcohol/chitosan sponge-like wound dressing: In vitro and in vivo studies [J].
Naseri-Nosar, Mahdi ;
Farzamfar, Saeed ;
Salehi, Majid ;
Vaez, Ahmad ;
Tajerian, Roksana ;
Azami, Mahmoud .
JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 2018, 33 (03) :269-281
[42]   Fabrication of chitosan-polyvinyl alcohol and silk electrospun fiber seeded with differentiated keratinocyte for skin tissue regeneration in animal wound model [J].
Fathi, Afshin ;
Khanmohammadi, Mehdi ;
Goodarzi, Arash ;
Foroutani, Lale ;
Mobarakeh, Zahra Taherian ;
Saremi, Jamileh ;
Arabpour, Zohreh ;
Ai, Jafar .
JOURNAL OF BIOLOGICAL ENGINEERING, 2020, 14 (01)
[43]   Electrospun Nanofibrous Biocomposite of Royal Jelly/Chitosan/Polyvinyl Alcohol (RJ/CS/PVA) Gel as a Biological Dressing for P. aeruginosa-Infected Burn Wound [J].
Ashrafi, Behnam ;
Chehelcheraghi, Farzaneh ;
Rashidipour, Marzieh ;
Hadavand, Samaneh ;
Beiranvand, Behrouz ;
Taherikalani, Morovat ;
Soroush, Setareh .
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2024, 196 (06) :3162-3183
[44]   In-vitro and in-vivo studies of Tridax procumbens leaf extract incorporated bilayer polycaprolactone/polyvinyl alcohol-chitosan electrospun nanofiber for wound dressing application [J].
Cheriyan, Silpa ;
Shin, Hwarang ;
Razack, Sirajunnisa Abdul ;
Kang, Myungji ;
Boopathi, T. S. ;
Kang, Hyun Wook ;
Mani, Karthega .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 299
[45]   Salt-resistant and antibacterial polyvinyl alcohol/chitosan/silver-loaded graphene oxide electrospun nanofiber membrane for high-efficiency solar-driven desalination [J].
Kang, Qianru ;
Zhai, Yiwei ;
Zhao, Fangbo ;
Yang, Liu ;
Yang, Ye ;
Park, Hee-Deung ;
Li, Zhiguo ;
Chen, Hongxu ;
Sun, Gaohui .
CHEMICAL ENGINEERING RESEARCH & DESIGN, 2024, 205 :107-117
[46]   Zingiber cassumunar Roxb. Essential Oil-Loaded Electrospun Poly(lactic acid)/Poly(ethylene oxide) Fiber Blend Membrane for Antibacterial Wound Dressing Application [J].
Sinsup, Pattawika ;
Teeranachaideekul, Veerawat ;
Makarasen, Arthit ;
Chuenchom, Laemthong ;
Prajongtat, Pongthep ;
Techasakul, Supanna ;
Yingyuad, Peerada ;
Dechtrirat, Decha .
MEMBRANES, 2021, 11 (09)
[47]   Electrospun film polyvinyl alcohol/chitosan loaded with cinnamon essential oil and inhibitory effects on polyphenol oxidase and dominant spoilage bacteria from Pacific white shrimp [J].
Zhang, Minzhen ;
Wang, Lin ;
Zou, Xiaoyu ;
Song, Ru .
FOOD HYDROCOLLOIDS, 2024, 156
[48]   Green Electrospun Poly(vinyl alcohol)/Gelatin-Based Nanofibrous Membrane by Incorporating 45S5 Bioglass Nanoparticles and Urea for Wound Dressing Applications: Characterization and In Vitro and In Vivo Evaluations [J].
Temel-Soylu, Tulay Merve ;
Kececiler-Emir, Ceren ;
Rababah, Taha ;
Ozel, Cem ;
Yucel, Sevil ;
Basaran-Elalmis, Yeliz ;
Altan, Dilan ;
Kirgiz, Omer ;
Secinti, Ilke Evrim ;
Kaya, Ufuk ;
Altug, Muhammed Enes .
ACS OMEGA, 2024, 9 (19) :21187-21203
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