Infantile bullous pemphigoid treated with intravenous immunoglobulin therapy

被引:29
作者
Sugawara, Nobuyuki [1 ]
Nagai, Yayoi [1 ]
Matsushima, Yoichiro [1 ]
Aoyama, Kumi [1 ]
Ishikawa, Osamu [1 ]
机构
[1] Gunma Univ, Grad Sch Med, Dept Dermatol, Maebashi, Gunma 3718511, Japan
关键词
D O I
10.1016/j.jaad.2007.08.005
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
A 3-month-old boy presented with a 2-week history of rapidly spreading skin rashes. Physical examination revealed generalized urticarial plaques with tense bullae and small vesicles. Histologic examination and immunofluorescence established the diagnosis of bullous pemphigoid. The disease was resistant to conventional therapies with the combination of corticosteroids, dapsone, and erythromycin. Finally, intravenous immunoglobulin therapy brought about a remarkable improvement. We suggest that intravenous immunoglobulin therapy is a valuable treatment option for intractable bullous pemphigoid in infants as well as in adults.
引用
收藏
页码:1084 / 1089
页数:6
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