Evaluation of Potential Mechanisms Underlying the Safety Observations of Filgotinib in Clinical Studies in RA

被引：0
|
作者：
Di Paolo, Julie [1 ]
Downie, Bryan [2 ]
Meng, Amy [3 ]
Mollova, Nevena [3 ]
Yu, Yuanjiang [3 ]
Han, Pei [3 ]
机构：
[1] Gilead Sci, Foster City, CA USA
[2] Gilead Sci Inc, Foster Citty, CA USA
[3] Gilead Sci Inc, 353 Lakeside Dr, Foster City, CA 94404 USA
来源：
ARTHRITIS & RHEUMATOLOGY | 2019年 / 71卷
关键词：
ACTIVE RHEUMATOID-ARTHRITIS; INHIBITOR; PHARMACOKINETICS; GLPG0634/GS-6034;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
0059
引用
收藏
页数：2
相关论文
共 50 条
  • [21] THE DIRECT VISUALIZATION OF BLOOD-FLOW BY REAL-TIME ULTRASOUND - CLINICAL OBSERVATIONS AND UNDERLYING MECHANISMS
    WOLVERSON, MK
    NOURI, S
    JOIST, JH
    SUNDARAM, M
    HEIBERG, E
    RADIOLOGY, 1981, 140 (02) : 443 - 448
  • [22] A systematic review on the safety of Psoraleae Fructus: potential risks, toxic characteristics, underlying mechanisms and detoxification methods
    SHI Zhuo
    GAO Jing
    PAN Jinchao
    ZHANG Zuqi
    ZHANG Guangchen
    WANG Yuguang
    GAO Yue
    Chinese Journal of Natural Medicines, 2022, 20 (11) : 805 - 813
  • [23] A systematic review on the safety of Psoraleae Fructus: potential risks, toxic characteristics, underlying mechanisms and detoxification methods
    She Zhuo
    Gao Ling
    Pan Jinchao
    Zhang Zuqi
    Zhang Guangchen
    Wang Yuguang
    Gao Yue
    CHINESE JOURNAL OF NATURAL MEDICINES, 2022, 20 (11) : 805 - 813
  • [24] Evaluation of potential mechanisms underlying genotype–phenotype correlations in multiple endocrine neoplasia type 2
    N Miše
    M Drosten
    T Racek
    A Tannapfel
    B M Pützer
    Oncogene, 2006, 25 : 6637 - 6647
  • [25] Evaluation of mechanisms underlying regenerative potential of cell sheets from human mesenchymal stromal cells
    Nimiritsky, P. P.
    Makarevich, O. A.
    Sagaradze, G. D.
    Efimenko, A. Y.
    Eremichev, R. Y.
    Makarevich, P. I.
    Tkachuk, V. A.
    HUMAN GENE THERAPY, 2017, 28 (12) : A100 - A100
  • [26] Evaluation of the therapeutic potential and underlying mechanisms of synephrine, a component of Kampo medicine, against allergic rhinitis
    Hommura, Tomoko
    Dan, Katsuaki
    Kanzaki, Sho
    Watanabe, Kenji
    Ogawa, Kaoru
    COGENT BIOLOGY, 2019, 5 (01):
  • [27] Studies on the variation in clinical laboratory data and safety evaluation of pharmaceuticals
    Nomura, M
    Hata, T
    Naitoh, S
    Kuwao, H
    Moriyama, K
    Fukuoka, M
    Kudo, M
    Tohda, Y
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2005, 125 (12): : 997 - 1004
  • [28] EFFICACY AND SAFETY OF BARICITINIB (BARI) IN RHEUMATOID ARTHRITIS(RA): CLINICAL AND ULTRASOUND EVALUATION IN REAL LIFE
    Tesei, G.
    Bruni, C.
    Cometi, L.
    Nacci, F.
    Capassoni, M.
    Terenzi, R.
    Tofani, L.
    Bartoli, F.
    Fiori, G.
    Matucci-Cerinic, M.
    ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 : 1477 - 1478
  • [29] Exploratory Analysis of Filgotinib Safety Data in Patients with Moderately to Severely Active RA and an Increased Risk of Cardiovascular Events: Data from Phase 2 and 3 Clinical Trials
    Buch, Maya
    Burmester, Gerd
    Mariette, Xavier
    Charles-Schoeman, Christina
    Rajendran, Vijay
    Stiers, Pieter-Jan
    Cerani, Agustin
    Van Hoek, Paul
    Van Beneden, Katrien
    Tanaka, Yoshiya
    Schulze-Koops, Hendrik
    Westhovens, Rene
    Favalli, Ennio Giulio
    ARTHRITIS & RHEUMATOLOGY, 2022, 74 : 523 - 525
  • [30] Underlying mechanisms of acupuncture therapy on polycystic ovary syndrome: Evidences from animal and clinical studies
    Ye, Yang
    Zhou, Cong-Cong
    Hu, Hang-Qi
    Fukuzawa, Ii
    Zhang, Hao-Lin
    FRONTIERS IN ENDOCRINOLOGY, 2022, 13
12345