Distribution of sulfamonomethoxine and trimethoprim in egg yolk and white

被引：13

作者：

Bilandzic, Nina ^{[1
]}

Bozic, Durdica ^{[1
]}

Kolanovic, Bozica Solomun ^{[1
]}

Varenina, Ivana ^{[1
]}

Cvetnic, Luka ^{[2
]}

Cvetnic, Zeljko ^{[3
]}

机构：

[1] Croatian Vet Inst, Lab Residue Control, Dept Vet Publ Hlth, HR-10000 Zagreb, Croatia

[2] Univ Zagreb, Fac Vet Med, Zagreb 41000, Croatia

[3] Croatian Vet Inst, Gen Dept, HR-10000 Zagreb, Croatia

来源：

FOOD CHEMISTRY | 2015年 / 178卷

关键词：

Sulfamonomethoxine; Trimethoprim; Elimination; Laying hens; Egg; Yolk; White; LC-MS/MS; SULFONAMIDE RESIDUES; LAYING HENS; SULFADIAZINE; SULFAQUINOXALINE; SULFADIMETHOXINE; DEPLETION; POULTRY; TISSUES;

D O I：

10.1016/j.foodchem.2015.01.076

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The distribution of sulfamonomethoxine (SMM) and trimethoprim (TMP) in egg yolk and white was measured during and after administration of a SMM/TMP combination in laying hens in doses of 8 gl(-1) and 12 g l(-1) in drinking water for 7 days. The SMM concentration reached maximal levels on day 2 of the post-treatment period for both doses (mu g kg(-1)): 5920 and 9453 in yolk; 4831 and 6050 in white, in doses 1 and 2, respectively. Significant differences in the SMM and TMP concentrations between yolk and white in post treatment period were found. SMM dropped below the LOD (1.9 mu g kg(-1)) in yolk after day 16 and 19 for doses 1 and 2. TMP reached maximal levels on day 3 after drug administration for doses 1 and 2 (mu g kg(-1)); 6521 and 7329 in yolk, 1370 and 1539 in white. TMP residues were measured above LOD (0.3 mu g kg(-1)) in yolk for both doses on day 37 post-treatment. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：32 / 37

页数：6

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