Nonenzymatic glucose sensor based on glassy carbon electrode modified with a nanocomposite composed of nickel hydroxide and graphene

被引：94
作者：
Qiao, Ningqiang [1 ]
Zheng, Jianbin [1 ]
机构：
[1] NW Univ Xian, Inst Analyt Sci, Shaanxi Prov Key Lab Electroanalyt Chem, Xian 710069, Shaanxi, Peoples R China
来源：
MICROCHIMICA ACTA | 2012年 / 177卷 / 1-2期
基金：
中国国家自然科学基金;
关键词：
Nonenzymatic sensor; Graphene; Glucose; Nickel hydroxide; ELECTROCATALYTIC OXIDATION; IONIC LIQUID; OXIDASE; NANOPARTICLES;
D O I：
10.1007/s00604-011-0756-3
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
We report on a nonenzymatic glucose sensor based on a glassy carbon electrode that was electrochemically modified with a nanocomposite prepared from nickel hydroxide and graphene. Scanning electron microscopy revealed that the nickel hydroxide in the nanocomposite was present in the form of a nanostructure of three-dimensional spheres that were assembled by many densely arranged nanosheets. The electrocatalytic activity of the electrode toward the oxidation of glucose was investigated by chronoamperometry. The current response was linearly related to the glucose concentration in the range from 1 to 10 mu M, with a sensitivity of 494 mu A mM(-1) cm(-2) and a correlation coefficient of 0.9990, and a second range (from 10 to 1000 mu M with a sensitivity of 328 mu A mM(-1) cm(-2) and a correlation coefficient of 0.9990). The detection limit was 0.6 mu M at a signal-to-noise ratio of 3, and the response time was as short as 2 s.
引用
收藏
页码：103 / 109
页数：7
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