Ciprofloxacin-loaded bovine serum albumin microspheres:: preparation and drug-release in vitro

被引：0
|
作者：
Li, FQ [1 ]
Hu, JH
Lu, B
Yao, H
Zhang, WG
机构：
[1] Second Mil Med Univ, Changhai Hosp, Dept Pharmaceut Sci, Shanghai 200433, Peoples R China
[2] W China Univ Med Sci, Sch Pharm, Chengdu 610041, Peoples R China
来源：
JOURNAL OF MICROENCAPSULATION | 2001年 / 18卷 / 06期
关键词：
ciprofloxacin; microspheres; spray drying; thermal denaturation; drug-release;
D O I：
暂无
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Ciprofloxacin albumin microspheres were prepared by the spray drying technique, with bovine serum albumin as the natural biodegradable wall material. The spherical microspheres, flowed well, were organic solvent free and in the size range 1 similar to 5 mum. The drug release from the microspheres could be retarded by further thermal denaturation. The sustained-release microspheres were suitable for dry powder inhaled lung drug delivery systems.
引用
收藏
页码：825 / 829
页数：5
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