Niobium (V) chloride catalyzed Knoevenagel condensation: An efficient protocol for the preparation of electrophilic alkenes

被引：80

作者：

Leelavathi, P ^{[1
]}

Kumar, SR ^{[1
]}

机构：

[1] Osmania Univ, Coll Women, Dept Chem, Hyderabad 500095, Andhra Pradesh, India

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2005年 / 240卷 / 1-2期

关键词：

aldehydes; active methylene compounds; Knoevenagel condensation; Lewis acid; electrophilic alkenes;

D O I：

10.1016/j.molcata.2005.06.026

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The condensation reaction has been carryout very conveniently to obtain the corresponding substituted olefins in excellent yields and showing all the products in excellent E-geometry. The reaction conditions are very mild and applicable to various aldehydes as well as active methylene compounds. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：99 / 102

页数：4

共 29 条

[1]

ABDALLAHELAYOUBI S, 1994, SYNTHESIS-STUTTGART, P258

[2] Niobium(V) chloride-mediated allylation of aldehydes. Scope and stereoselectivity [J].

Andrade, CKZ ;

Azevedo, NR .

TETRAHEDRON LETTERS, 2001, 42 (37) :6473-6476

[3] A simple and regioselective carbon-oxygen bond cleavage using niobium(V) [J].

Arai, S ;

Sudo, Y ;

Nishida, A .

SYNLETT, 2004, (06) :1104-1106

[4]

BASTUS JB, 1963, TETRAHEDRON LETT, P955

[5] Montmorillonite KSF as an inorganic, water stable, and reusable catalyst for the knoevenagel synthesis of coumarin-3-carboxylic acids [J].

Bigi, F ;

Chesini, L ;

Maggi, R ;

Sartori, G .

JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (03) :1033-1035

[6]

Bose DS, 2001, J CHEM RES, P36

[7] KNOEVENAGEL CONDENSATION IN THE HETEROGENEOUS PHASE USING ALPO4-AL2O3 AS A NEW CATALYST [J].

CABELLO, JA ;

CAMPELO, JM ;

GARCIA, A ;

LUNA, D ;

MARINAS, JM .

JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (26) :5195-5197

[8] A straightforward method for the synthesis of alkylidene and arylidene malonates through proline-catalyzed knoevenagel condensation [J].

Cardillo, G ;

Fabbroni, S ;

Gentilucci, L ;

Gianotti, M ;

Tolomelli, A .

SYNTHETIC COMMUNICATIONS, 2003, 33 (09) :1587-1594

[9] Group 5 and group 6 metal halides as very efficient catalysts for acylative cleavage of ethers [J].

Guo, QX ;

Miyaji, T ;

Hara, R ;

Shen, BJ ;

Takahashi, T .

TETRAHEDRON, 2002, 58 (36) :7327-7334

[10] Lewis acidic ionic liquids for the synthesis of electrophilic alkenes via the Knoevenagel condensation [J].

Harjani, JR ;

Nara, SJ ;

Salunkhe, MM .

TETRAHEDRON LETTERS, 2002, 43 (06) :1127-1130

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