Viability of a capsule- and lipopolysaccharide-deficient mutant of Neisseria meningitidis

被引：47
作者：
Bos, MP
Tommassen, J
机构：
[1] Univ Utrecht, Dept Mol Microbiol, NL-3584 CH Utrecht, Netherlands
[2] Univ Utrecht, Inst Biomembranes, NL-3584 CH Utrecht, Netherlands
来源：
INFECTION AND IMMUNITY | 2005年 / 73卷 / 09期
关键词：
D O I：
10.1128/IAI.73.9.6194-6197.2005
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Neisseria meningitidis is the only lipopolysaccharide (LPS)-producing gram-negative bacterial species shown to be viable also without LPS. It was thought that the presence of capsular polysaccharide is necessary for this unusual feature. However, we show now that no part of the capsule gene cluster is required for maintaining LPS deficiency in N. meningitidis.
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收藏
页码：6194 / 6197
页数：4
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