Assay to rapidly screen for immunoglobulin light chain glycosylation: a potential path to earlier AL diagnosis for a subset of patients

被引:60
作者
Kumar, Sanjay [1 ]
Murray, David [2 ]
Dasari, Surendra [3 ]
Milani, Paolo [4 ,5 ]
Barnidge, David [2 ]
Madden, Benjamin [6 ]
Kourelis, Taxiarchis [1 ]
Arendt, Bonnie [2 ]
Merlini, Giampaolo [4 ,5 ]
Ramirez-Alvarado, Marina [7 ]
Dispenzieri, Angela [1 ,2 ]
机构
[1] Mayo Clin, Div Hematol, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Lab Med, Rochester, MN 55905 USA
[3] Mayo Clin, Dept Hlth Sci, Rochester, MN USA
[4] Univ Pavia, Amyloidosis Res & Treatment Ctr, Fdn IRCCS Policlin San Matteo, Pavia, Italy
[5] Univ Pavia, Dept Mol Med, Pavia, Italy
[6] Mayo Clin, Med Genom Facil, Prote Core, Rochester, MN USA
[7] Mayo Clin, Dept Biochem & Mol Biol, Rochester, MN USA
关键词
VARIABLE REGION; GENE USAGE; CARBOHYDRATE; AMYLOIDOSIS;
D O I
10.1038/s41375-018-0194-x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:254 / 257
页数:4
相关论文
共 15 条
[1]   Monitoring free light chains in serum using mass spectrometry [J].
Barnidge, David R. ;
Dispenzieri, Angela ;
Merlini, Giampaolo ;
Katzmann, Jerry A. ;
Murray, David L. .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2016, 54 (06) :1073-1083
[2]   Review: Immunoglobulin light chain amyloidosis - The archetype of structural and pathogenic variability [J].
Bellotti, V ;
Mangione, P ;
Merlini, G .
JOURNAL OF STRUCTURAL BIOLOGY, 2000, 130 (2-3) :280-289
[3]   Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic κ1 immunoglobulin light chains [J].
Connors, Lawreen H. ;
Jiang, Yan ;
Budnik, Marianna ;
Theberge, Roger ;
Prokaeva, Tatiana ;
Bodi, Kip L. ;
Seldin, David C. ;
Costello, Catherine E. ;
Skinner, Martha .
BIOCHEMISTRY, 2007, 46 (49) :14259-14271
[4]   Proteomic Detection of Immunoglobulin Light Chain Variable Region Peptides from Amyloidosis Patient Biopsies [J].
Dasari, Surendra ;
Theis, Jason D. ;
Vrana, Julie A. ;
Meureta, Oana M. ;
Quint, Patrick S. ;
Muppa, Prasuna ;
Zenka, Roman M. ;
Tschumper, Renee C. ;
Jelinek, Diane F. ;
Davila, Jaime I. ;
Sarangi, Vivekananda ;
Kurtin, Paul J. ;
Dogan, Ahmet .
JOURNAL OF PROTEOME RESEARCH, 2015, 14 (04) :1957-1967
[5]   POLYMORPHISM IN A KAPPA I PRIMARY (AL) AMYLOID PROTEIN (BAN) [J].
DWULET, FE ;
OCONNOR, TP ;
BENSON, MD .
MOLECULAR IMMUNOLOGY, 1986, 23 (01) :73-78
[6]   Screening Method for M-Proteins in Serum Using Nanobody Enrichment Coupled to MALDI-TOF Mass Spectrometry [J].
Kohlhagen, Mindy C. ;
Barnidge, David R. ;
Mills, John R. ;
Stoner, Joshua ;
Gurtner, Kari M. ;
Liptac, Andrea M. ;
Lofgren, Denise I. ;
Vanderboom, Patrick M. ;
Dispenzieri, Angela ;
Katzmann, Jerry A. ;
Willrich, Maria A. V. ;
Snyder, Melissa R. ;
Murray, David L. .
CLINICAL CHEMISTRY, 2016, 62 (10) :1345-1352
[7]   Clarifying immunoglobulin gene usage in systemic and localized immunoglobulin light-chain amyloidosis by mass spectrometry [J].
Kourelis, Taxiarchis V. ;
Dasari, Surendra ;
Theis, Jason D. ;
Ramirez-Alvarado, Marina ;
Kurtin, Paul J. ;
Gertz, Morie A. ;
Zeldenrust, Steven R. ;
Zenka, Roman M. ;
Dogan, Ahmet ;
Dispenzieri, Angela .
BLOOD, 2017, 129 (03) :299-306
[8]   The utility of MASS-FIX to detect and monitor monoclonal proteins in the clinic [J].
Milani, Paolo ;
Murray, David L. ;
Barnidge, David R. ;
Kohlhagen, Mindy C. ;
Mills, John R. ;
Merlini, Giampaolo ;
Dasari, Surendra ;
Dispenzieri, Angela .
AMERICAN JOURNAL OF HEMATOLOGY, 2017, 92 (08) :772-779
[9]   STRUCTURES OF THE CARBOHYDRATE MOIETIES OF 2 MONOCLONAL HUMAN LAMBDA-TYPE IMMUNOGLOBULIN LIGHT-CHAINS [J].
OHKURA, T ;
ISOBE, T ;
YAMASHITA, K ;
KOBATA, A .
BIOCHEMISTRY, 1985, 24 (02) :503-508
[10]   Glycosylation in cancer: mechanisms and clinical implications [J].
Pinho, Salome S. ;
Reis, Celso A. .
NATURE REVIEWS CANCER, 2015, 15 (09) :540-555