Metabolic Syndrome and psoriatic arthritis: considerations for the clinician

被引：28

作者：

Caso, Francesco ^{[1
]}

Chimenti, Maria Sole ^{[2
]}

Navarini, Luca ^{[3
]}

Ruscitti, Piero ^{[4
]}

Peluso, Rosario ^{[1
]}

Girolimetto, Nicolo ^{[1
,5
]}

Del Puente, Antonio ^{[1
]}

Giacomelli, Roberto ^{[4
]}

Scarpa, Raffaele ^{[1
]}

Costa, Luisa ^{[1
]}

机构：

[1] Univ Federico II, Dept Clin Med & Surg, Rheumatol Unit, Via Sergio Pansini 5, I-80131 Naples, Italy

[2] Univ Roma Tor Vergata, Dept Syst Med, Rheumatol Allergol & Clin Immunol, Rome, Italy

[3] Univ Campus Biomed Roma, Unit Allergol Clin Immunol & Rheumatol, Rome, Italy

[4] Univ Aquila, Dept Biotechnol & Appl Clin Sci, Rheumatol Unit, Laquila, Italy

[5] Azienda USL IRCCS Reggio Emilia, Dept Rheumatol, Reggio Emilia, Italy

来源：

EXPERT REVIEW OF CLINICAL IMMUNOLOGY | 2020年 / 16卷 / 04期

关键词：

Psoriatic arthritis; Metabolic Syndrome; cardiovascular risk; obesity; adipokines; CARDIOVASCULAR RISK-FACTORS; QUALITY-OF-LIFE; CONTRAST-ENHANCED ULTRASOUND; DISEASE-ACTIVITY STATE; BODY-MASS INDEX; RHEUMATOID-ARTHRITIS; SUBCLINICAL ATHEROSCLEROSIS; TNF-ALPHA; PHARMACOLOGICAL-TREATMENT; ANKYLOSING-SPONDYLITIS;

D O I：

10.1080/1744666X.2020.1740593

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Introduction: Metabolic Syndrome (MetS) is strictly interconnected with systemic inflammation, and increased evidence has described a close link between this condition and Psoriatic Arthritis (PsA). Areas covered: This review summarizes main studies exploring clinical aspects and prevalence of MetS in PsA cohorts. Further, there is accumulating evidence showing shared inflammatory pathways between MetS, its components, and PsA. Expert opinion: The high prevalence of MetS in PsA highlights the need for screening, evaluation, and close monitoring of MetS and its components (namely, diabetes mellitus, obesity, hypertension, and dyslipidemia) in psoriatic patients. Further studies should focus on the pathogenetic link between MetS and PsA. More studies are required to identify appropriate algorithms for the assessment and management of MetS in PsA patients.

引用

页码：409 / 420

页数：12

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