Effect of Graphene Oxide and Carbon Nanotubes on the Reaction of Tritium Atoms with Dalargin

Effect of carbon substrates materials (graphene oxide, reduced graphene oxide, single-walled carbon nanotubes) on the result of tritium introduction into dalargin peptide was studied by the thermal activation method. It was shown that, when dalargin is deposited onto carbon substrates, the distribution of tritium over amino-acid residues strongly changes as compared with a thick target deposited directly onto glass walls of a vessel. It was demonstrated that, when dalargin is deposited onto the carbon materials studied, the content of tritium in phenylalanine substantially increases, which indicates that the isotope exchange reaction occurs by the electrophilic mechanism. It was also found that the content of tritium in other amino-acid residues substantially changes, which is due to the difference between the structures of adsorption layers of the peptide, formed n the carbon materials under consideration.