Inertial focusing of non-spherical microparticles

被引:114
作者
Hur, Soojung Claire [1 ,2 ]
Choi, Sung-Eun [3 ,4 ]
Kwon, Sunghoon [3 ]
Di Carlo, Dino [2 ,5 ]
机构
[1] Univ Calif Los Angeles, Dept Mech & Aerosp Engn, Los Angeles, CA 90095 USA
[2] Calif NanoSyst Inst, Los Angeles, CA 90095 USA
[3] Seoul Natl Univ, Dept Elect Engn, Seoul 151742, South Korea
[4] Seoul Natl Univ, Interuniv Semicond Res Ctr, Seoul 151742, South Korea
[5] Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
基金
美国国家科学基金会;
关键词
PARTICLES; FILTRATION;
D O I
10.1063/1.3608115
中图分类号
O59 [应用物理学];
学科分类号
摘要
We have investigated the focusing and dynamics of non-spherical polymeric particles in microfluidic flows at finite Reynolds number. The rotational diameter, D-max, of a particle, regardless of its cross-sectional shape, was found to determine the final focused position, except for the case of asymmetric disks. Additionally, elongated particles with larger D-max exhibited longer residence times in a horizontal orientation than those with smaller D-max. These findings inform approaches to hydrodynamically control shaped and barcoded particles for multiplexed biochemical assays. (C) 2011 American Institute of Physics. [doi:10.1063/1.3608115]
引用
收藏
页数:3
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