Chloroquine and COVID-19: A Light at the End of the Tunnel, or is it Another Train?

被引：8

作者：

Aljofan, Mohamad ^{[1
]}

Gaipov, Abduzhappar ^{[1
]}

机构：

[1] Nazarbayev Univ, Sch Med, Nur Sultan, Kazakhstan

来源：

ELECTRONIC JOURNAL OF GENERAL MEDICINE | 2020年 / 17卷 / 04期

关键词：

COVID-19; INFECTION; VIRUS;

D O I：

10.29333/ejgm/7863

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Over the last a few decades, the world has faced several viral disease outbreaks including Hendra, Nipah, severe acute respiratory syndrome (SARS), Influenza (H1N1), Middle East respiratory syndrome (MERS), Zika and most recently coronavirus disease 2019 (COVID-19). The economical and health impacts of the outbreaks were limited to certain affected areas only, but the recent outbreak of COVID-19 seems to have a global impact on human health, health resources and global economy.

引用

收藏

页数：2

相关论文

共 7 条

[1] Chloroquine and hydroxychloroquine as available weapons to fight COVID-19 [J].

Colson, Philippe ;

Rolain, Jean-Marc ;

Lagier, Jean-Christophe ;

Brouqui, Philippe ;

Raoult, Didier .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2020, 55 (04)

[2] EFFECTS OF CHLOROQUINE AND CYTOCHALASIN-B ON THE INFECTION OF CELLS BY SINDBIS VIRUS AND VESICULAR STOMATITIS-VIRUS [J].

COOMBS, K ;

MANN, E ;

EDWARDS, J ;

BROWN, DT .

JOURNAL OF VIROLOGY, 1981, 37 (03) :1060-1065

[3] Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies [J].

Gao, Jianjun ;

Tian, Zhenxue ;

Yang, Xu .

BIOSCIENCE TRENDS, 2020, 14 (01) :72-73

[4] The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 [J].

Gorbalenya, Alexander E. ;

Baker, Susan C. ;

Baric, Ralph S. ;

de Groot, Raoul J. ;

Drosten, Christian ;

Gulyaeva, Anastasia A. ;

Haagmans, Bart L. ;

Lauber, Chris ;

Leontovich, Andrey M. ;

Neuman, Benjamin W. ;

Penzar, Dmitry ;

Perlman, Stanley ;

Poon, Leo L. M. ;

Samborskiy, Dmitry V. ;

Sidorov, Igor A. ;

Sola, Isabel ;

Ziebuhr, John .

NATURE MICROBIOLOGY, 2020, 5 (04) :536-544

[5] Simulating Henipavirus Multicycle Replication in a Screening Assay Leads to Identification of a Promising Candidate for Therapy [J].

Porotto, Matteo ;

Orefice, Gianmarco ;

Yokoyama, Christine C. ;

Mungall, Bruce A. ;

Realubit, Ronald ;

Sganga, Michael L. ;

Aljofan, Mohamad ;

Whitt, Michael ;

Glickman, Fraser ;

Moscona, Anne .

JOURNAL OF VIROLOGY, 2009, 83 (10) :5148-5155

[6] Chloroquine is a potent inhibitor of SARS coronavirus infection and spread [J].

Vincent, Martin J. ;

Bergeron, Eric ;

Benjannet, Suzanne ;

Erickson, Bobbie R. ;

Rollin, Pierre E. ;

Ksiazek, Thomas G. ;

Seidah, Nabil G. ;

Nichol, Stuart T. .

VIROLOGY JOURNAL, 2005, 2 (1)

[7] Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model [J].

Yan, Yiwu ;

Zou, Zhen ;

Sun, Yang ;

Li, Xiao ;

Xu, Kai-Feng ;

Wei, Yuquan ;

Jin, Ningyi ;

Jiang, Chengyu .

CELL RESEARCH, 2013, 23 (02) :300-302