Capsaicin induces CYP3A2 via pregnane X receptor pathway

被引：0
|
作者：
Higashitani, A. [1 ]
Takano, M. [1 ]
Urashima, Y. [1 ]
Kato, R. [1 ]
Ijiri, Y. [1 ]
Tanaka, K. [1 ]
机构：
[1] Osaka Univ Pharmaceut Sci, Takatsuki, Osaka, Japan
来源：
THERAPEUTIC DRUG MONITORING | 2011年 / 33卷 / 04期
关键词：
CYP3A2; capsaicin; induction; lipopolysaccharide; pregnane X receptor;
D O I：
暂无
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：554 / 554
页数：1
相关论文
共 50 条
  • [21] Scutellarin Mediates Cytochrome P450 3A4 and 2C19 Expression via Pregnane X Receptor and Constitutive Androstane Receptor
    Huang, Hangxing
    Cao, Change
    Miao, Zhimin
    Yang, Xiaoli
    Lai, Yong
    CURRENT MOLECULAR PHARMACOLOGY, 2023, 16 (06) : 640 - 653
  • [22] Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro
    Feng, Dandan
    Tang, Tao
    Fan, Rong
    Luo, Jiekun
    Cui, Hanjin
    Wang, Yang
    Gan, Pingping
    BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 18
  • [23] Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro
    Dandan Feng
    Tao Tang
    Rong Fan
    Jiekun Luo
    Hanjin Cui
    Yang Wang
    Pingping Gan
    BMC Complementary and Alternative Medicine, 18
  • [24] Polycyclic Aromatic Hydrocarbons Activate CYP3A4 Gene Transcription through Human Pregnane X Receptor
    Kumagai, Takeshi
    Suzuki, Hiroyuki
    Sasaki, Takamitsu
    Sakaguchi, Shuhei
    Miyairi, Shinichi
    Yamazoe, Yasushi
    Nagata, Kiyoshi
    DRUG METABOLISM AND PHARMACOKINETICS, 2012, 27 (02) : 200 - 206
  • [25] Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding
    Istrate, Monica A.
    Nussler, Andreas K.
    Eichelbaum, Michel
    Burk, Oliver
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2010, 393 (04) : 688 - 693
  • [26] Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat
    Ibrahim, Zein Shaban
    Ahmed, Mohamed Mohamed
    El-Shazly, Samir Ahmed
    Ishizuka, Mayumi
    Fujita, Shoichi
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2014, 78 (09) : 1550 - 1559
  • [27] Vitamin E activates gene expression via the pregnane X receptor
    Landes, N
    Pfluger, P
    Kluth, D
    Birringer, M
    Rühl, R
    Böl, GF
    Glatt, H
    Brigelius-Flohé, R
    BIOCHEMICAL PHARMACOLOGY, 2003, 65 (02) : 269 - 273
  • [28] Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway
    Lau, Jamie K.
    Brown, Kathleen C.
    Dom, Aaron M.
    Witte, Theodore R.
    Thornhill, Brent A.
    Crabtree, Clayton M.
    Perry, Haley E.
    Brown, J. Michael
    Ball, John G.
    Creel, Rebecca G.
    Damron, C. Luke
    Rollyson, William D.
    Stevenson, Cathryn D.
    Hardman, W. Elaine
    Valentovic, Monica A.
    Carpenter, A. Betts
    Dasgupta, Piyali
    APOPTOSIS, 2014, 19 (08) : 1190 - 1201
  • [29] Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway
    Jamie K. Lau
    Kathleen C. Brown
    Aaron M. Dom
    Theodore R. Witte
    Brent A. Thornhill
    Clayton M. Crabtree
    Haley E. Perry
    J. Michael Brown
    John G. Ball
    Rebecca G. Creel
    C. Luke Damron
    William D. Rollyson
    Cathryn D. Stevenson
    W. Elaine Hardman
    Monica A. Valentovic
    A. Betts Carpenter
    Piyali Dasgupta
    Apoptosis, 2014, 19 : 1190 - 1201
  • [30] Melatonin attenuates lipopolysaccharide-induced down-regulation of pregnane X receptor and its target gene CYP3A in mouse liver
    Xu, DX
    Wei, W
    Sun, MF
    Wei, LZ
    Wang, JP
    JOURNAL OF PINEAL RESEARCH, 2005, 38 (01) : 27 - 34
12345