Capsaicin induces CYP3A2 via pregnane X receptor pathway

被引：0
|
作者：
Higashitani, A. [1 ]
Takano, M. [1 ]
Urashima, Y. [1 ]
Kato, R. [1 ]
Ijiri, Y. [1 ]
Tanaka, K. [1 ]
机构：
[1] Osaka Univ Pharmaceut Sci, Takatsuki, Osaka, Japan
来源：
THERAPEUTIC DRUG MONITORING | 2011年 / 33卷 / 04期
关键词：
CYP3A2; capsaicin; induction; lipopolysaccharide; pregnane X receptor;
D O I：
暂无
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：554 / 554
页数：1
相关论文
共 50 条
  • [1] Capsaicin induces CYP3A4 expression via pregnane X receptor and CCAAT/enhancer-binding protein β activation
    Han, Eun Hee
    Kim, Hyung Gyun
    Choi, Jae Ho
    Jang, Yin-Jin
    Lee, Sang Seop
    Kwon, Kwang-il
    Kim, Eunyoung
    Noh, Kyeumhan
    Jeong, Tae Cheon
    Hwang, Yong Pil
    Chung, Young Chul
    Kang, Wonku
    Jeong, Hye Gwang
    MOLECULAR NUTRITION & FOOD RESEARCH, 2012, 56 (05) : 797 - 809
  • [2] Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor
    Casabar, Richard C. T.
    Das, Parikshit C.
    DeKrey, Gregory K.
    Gardiner, Catherine S.
    Cao, Yan
    Rose, Randy L.
    Wallace, Andrew D.
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2010, 245 (03) : 335 - 343
  • [3] Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats
    Bi, Guofang
    Liang, Fengting
    Wu, Ting
    Wang, Peng
    Jiang, Xiaowen
    Hu, Shuang
    Wu, Chenghua
    Zhou, Wenhong
    Guo, Jiayin
    Yang, Xiao
    Fang, Jian-hong
    Chen, Wenying
    Bi, Huichang
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2024, 135 (02) : 148 - 163
  • [4] Baicalein ameliorates lipid accumulation in HepG2 cells via the pregnane X receptor signaling pathway
    Jiang, Qiuyan
    Zhang, Tiehua
    Liang, Yuan
    Zhang, Jie
    FOOD BIOSCIENCE, 2024, 60
  • [5] Resveratrol Suppresses the Inducible Expression of CYP3A4 Through the Pregnane X Receptor
    Deng, Rongrong
    Xu, Chenshu
    Chen, Xiao
    Chen, Pan
    Wang, Yongtao
    Zhou, Xunian
    Jin, Jing
    Niu, Lu
    Ying, Mengjia
    Huang, Min
    Bi, Huichang
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014, 126 (02) : 146 - 154
  • [6] Pregnane X receptor is required for IFN-α-mediated CYP3A29 expression in pigs
    Li, Xiaowen
    Jin, Xiue
    Zhou, Xiaoqiao
    Wang, Xiliang
    Shi, Deshi
    Xiao, Yuncai
    Bi, Dingren
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 445 (02) : 469 - 474
  • [7] Role of Pregnane X Receptor and Aryl Hydrocarbon Receptor in Transcriptional Regulation of pxr, CYP2, and CYP3 Genes in Developing Zebrafish
    Kubota, Akira
    Goldstone, Jared V.
    Lemaire, Benjamin
    Takata, Matthew
    Woodin, Bruce R.
    Stegeman, John J.
    TOXICOLOGICAL SCIENCES, 2015, 143 (02) : 398 - 407
  • [8] Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway
    Awortwe, Charles
    Manda, Vamshi K.
    Avonto, Cristina
    Khan, Shabana I.
    Khan, Ikhlas A.
    Walker, Larry A.
    Bouic, Patrick J.
    Rosenkranz, Bernd
    XENOBIOTICA, 2015, 45 (03) : 218 - 229
  • [9] Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways
    Cerveny, Lukas
    Svecova, Lucie
    Anzenbacherova, Eva
    Vrzal, Radim
    Staud, Frantisek
    Dvorak, Zdenek
    Ulrichova, Jitka
    Anzenbacher, Pavel
    Pavek, Petr
    DRUG METABOLISM AND DISPOSITION, 2007, 35 (07) : 1032 - 1041
  • [10] Perinatal lipopolysaccharide exposure downregulates pregnane X receptor and Cyp3a11 expression in fetal mouse liver
    Xu, DX
    Chen, YH
    Wang, JP
    Sun, MF
    Wang, H
    Wei, LZ
    Wei, W
    TOXICOLOGICAL SCIENCES, 2005, 87 (01) : 38 - 45
12345