Lupus anticoagulant in a child with celiac disease: a rare association

被引:2
作者
Naseem, Shano [1 ]
Suri, Deepti [1 ]
Ahluwalia, Jasmina [2 ]
Lal, Sadhna Bhasin [3 ]
Thapa, B. R. [3 ]
Singh, Surjit [1 ]
机构
[1] Postgrad Inst Med Educ & Res, Adv Pediat Ctr, Div Allergy & Immunol, Chandigarh 160012, India
[2] Postgrad Inst Med Educ & Res, Dept Hematol, Chandigarh 160012, India
[3] Postgrad Inst Med Educ & Res, Div Pediat Gastroenterol, Dept Gastroenterol, Chandigarh 160012, India
关键词
Celiac disease; Lupus anticoagulant; Antiphospholipid antibody; Pediatric; ANTIPHOSPHOLIPID ANTIBODIES; ERYTHEMATOSUS; DISORDERS;
D O I
10.1007/s00296-010-1669-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Celiac disease or gluten-sensitive enteropathy is characterized by malabsorption, chronic inflammation of the small intestine mucosa, villous atrophy and crypt hyperplasia. Association of auto-immunity has been reported to be almost threefold higher in patients with celiac disease. While there are several reports of celiac disease in association with autoimmune diseases, there is paucity of literature on its association with antiphospholipid antibodies. We report here an 8-year-old girl child with celiac disease who was found to have lupus anticoagulant positivity, an extremely uncommon association. This child is perhaps the youngest ever patient of celiac disease in association with lupus anticoagulant.
引用
收藏
页码:963 / 965
页数:3
相关论文
共 12 条
[1]   Antiphospholipid antibodies in children with systemic lupus erythematosus: a prospective study in northern India [J].
Ahluwalia, J ;
Singh, S ;
Garewal, G .
RHEUMATOLOGY INTERNATIONAL, 2005, 25 (07) :530-535
[2]  
CHIURAZZI F, 1987, HAEMATOLOGICA, V72, P257
[3]   A new method for characterization and epitope determination of a lupus anticoagulant-associated neutralizing antiprothrombin antibody [J].
Cote, HCF ;
Huntsman, DG ;
Wu, J ;
Wadsworth, LD ;
MacGillivray, RTA .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1997, 107 (02) :197-205
[4]   Fortnightly review - Coeliac disease [J].
Feighery, C .
BMJ-BRITISH MEDICAL JOURNAL, 1999, 319 (7204) :236-239
[5]   Systemic lupus erythematosus, celiac disease and antiphospholipid antibody syndrome: a rare association [J].
Gupta, Deepak ;
Mirza, Naureen .
RHEUMATOLOGY INTERNATIONAL, 2008, 28 (11) :1179-1180
[6]  
La Villa G, 2003, WORLD J GASTROENTERO, V9, P1377
[7]   Medical progress: The antiphospholipid syndrome. [J].
Levine, JS ;
Branch, DW ;
Rauch, J .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (10) :752-763
[8]  
Mean R T., 2009, Wintrobes Clinical hematology, V12th, P779
[9]  
PATRICIA G, 2007, REV COL GASTROENTROL, V22, P83
[10]   Antiphospholipid antibodies in children with Henoch-Schonlein purpura: a prospective study from North India [J].
Salhan, M. ;
Ahluwalia, J. ;
Singh, S. ;
Minz, R. W. .
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2007, 36 (06) :482-484