The copper-zinc superoxide dismutase activity in selected diseases

被引：72
|
作者：
Lewandowski, Lukasz [1 ]
Kepinska, Marta [1 ]
Milnerowicz, Halina [1 ]
机构：
[1] Wroclaw Med Univ, Div Lab Diagnost, Fac Pharm, Dept Biomed & Environm Anal, Wroclaw, Poland
来源：
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 2019年 / 49卷 / 01期
关键词：
copper-zinc superoxide dismutase; enzyme activity; single-nucleotide polymorphism; INCREASED OXIDATIVE STRESS; DIABETES-MELLITUS; CARDIOVASCULAR-DISEASE; GENETIC POLYMORPHISMS; ANTIOXIDANT DEFENSES; LIPID-PEROXIDATION; SKELETAL-MUSCLE; RENAL INJURY; EXPRESSION; COPD;
D O I：
10.1111/eci.13036
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Copper-zinc superoxide dismutase (Cu,Zn-SOD) plays a protective role in various types of tissue protecting them from oxidative damage. Alterations in Cu,Zn-SOD (SOD1 and SOD3) activity and its expression have been observed in pathological occurrences most prevalent in modern society, including inflammatory bowel disease, obesity and its implications-diabetes and hypertension, and chronic obstructive pulmonary disease. Moreover, several SOD1 and SOD3 gene polymorphisms have been associated with the risk of developing a particular type of disease, or its exacerbation. This article features recent observations in this topic, aiming to show the importance of proper gene sequence and activity of Cu,Zn-SOD in the aforementioned diseases.
引用
收藏
页数：10
相关论文
共 50 条
  • [1] Inhibition of copper-zinc superoxide dismutase activity by selected environmental xenobiotics
    Lewandowski, Lukasz
    Kepinska, Marta
    Milnerowicz, Halina
    ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2018, 58 : 105 - 113
  • [2] THE COPPER-ZINC SUPEROXIDE-DISMUTASE
    FEE, JA
    METAL IONS IN BIOLOGICAL SYSTEMS, 1981, 13 : 259 - 298
  • [3] Copper-zinc superoxide dismutase and ALS
    Valentine, JS
    Hart, PJ
    Gralla, EB
    COPPER TRANSPORT AND ITS DISORDERS: MOLECULAR AND CELLULAR ASPECTS, 1999, 448 : 193 - 203
  • [4] Copper-zinc superoxide dismutase and ALS
    Valentine, JS
    Gralla, EB
    Goto, JJ
    Liu, HB
    Zhu, HI
    JOURNAL OF INORGANIC BIOCHEMISTRY, 1999, 74 (1-4) : 55 - 55
  • [5] COPPER AND COPPER-ZINC SUPEROXIDE-DISMUTASE
    VALENTINE, JS
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1983, 186 (AUG): : 229 - INOR
  • [6] Identification of the copper-zinc superoxide dismutase activity in Mycoplasma hyopneumoniae
    Chen, JR
    Weng, CN
    Ho, TY
    Cheng, IC
    Lai, SS
    VETERINARY MICROBIOLOGY, 2000, 73 (04) : 301 - 310
  • [7] ROLE OF MAGNESIUM IN COPPER-ZINC SUPEROXIDE-DISMUTASE ACTIVITY
    KUMAR, M
    SULEIMAN, AA
    DODSON, W
    JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 1994, 13 (05) : 535 - 535
  • [8] Copper-zinc superoxide dismutase: friend or foe?
    Valentine, JS
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2001, 86 (01) : 8 - 8
  • [9] SPECTROELECTROCHEMISTRY OF COPPER-ZINC SUPEROXIDE-DISMUTASE
    STCLAIR, CS
    GRAY, HB
    VALENTINE, JS
    INORGANIC CHEMISTRY, 1992, 31 (05) : 925 - 927
  • [10] Copper-zinc superoxide dismutase and ALS.
    Valentine, JS
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 226 : U763 - U763
12345