The application of gold nanoparticles as a promising therapeutic approach in breast and ovarian cancer

被引:25
作者
Kafshdooz, Leila [2 ,4 ]
Kafshdooz, Taiebeh [2 ,3 ]
Razban, Zohreh [1 ]
Akbarzadeh, Abolfazl [1 ,2 ,3 ]
机构
[1] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz 5154853431, Iran
[2] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz, Iran
[3] Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz, Iran
[4] Tabriz Univ Med Sci, Liver & Gastrointestinal Dis Res Ctr, Tabriz, Iran
关键词
breast; cancer; gold; nanoparticle; ovary; PLASMON ABSORPTION; COLLOIDAL GOLD; GROWTH-FACTOR; SIZE; DNA; DEPENDENCE; RADIOTHERAPY; NANOCARRIERS; RESISTANCE; DIAGNOSIS;
D O I
10.3109/21691401.2015.1029625
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The development of specialized nanoparticles (NPs) for use in the detection and treatment of cancer is increasing. In the last few years, gold nanoparticles (AuNPs) have been greatly studied in biological and photothermal therapeutic status. AuNPs can bind to a wide range of organic molecules, and their synthesis is easy. In this review, we summarize the characteristics of AuNPs, their contributions to tumor destruction, their toxicity, and their potential in the treatment of breast and ovarian cancer.
引用
收藏
页码:1222 / 1227
页数:6
相关论文
共 69 条
  • [1] Ovarian cancer: Strategies for overcoming resistance to chemotherapy
    Agarwal, R
    Kaye, SB
    [J]. NATURE REVIEWS CANCER, 2003, 3 (07) : 502 - 516
  • [2] [Anonymous], J NANOMATERIALS
  • [3] Effect of Nanoparticle Surface Charge at the Plasma Membrane and Beyond
    Arvizo, Rochelle R.
    Miranda, Oscar R.
    Thompson, Michael A.
    Pabelick, Christina M.
    Bhattacharya, Resham
    Robertson, J. David
    Rotello, Vincent M.
    Prakash, Y. S.
    Mukherjee, Priyabrata
    [J]. NANO LETTERS, 2010, 10 (07) : 2543 - 2548
  • [4] Baptista PV, 2012, EXPERT REV MOL DIAGN, V12, P541, DOI [10.1586/erm.12.50, 10.1586/ERM.12.50]
  • [5] Gold nanoparticle size controlled by polymeric Au(I) thiolate precursor size
    Brinas, Raymond P.
    Hu, Minghui
    Qian, Luping
    Lymar, Elena S.
    Hainfeld, James F.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (03) : 975 - 982
  • [6] Nanoshells: gifts in a gold wrapper
    Brongersma, ML
    [J]. NATURE MATERIALS, 2003, 2 (05) : 296 - 297
  • [7] Angiogenesis in cancer and other diseases
    Carmeliet, P
    Jain, RK
    [J]. NATURE, 2000, 407 (6801) : 249 - 257
  • [8] Design and Characterization of HER-2-Targeted Gold Nanoparticles for Enhanced X-radiation Treatment of Locally Advanced Breast Cancer
    Chattopadhyay, Niladri
    Cai, Zhongli
    Pignol, Jean-Philippe
    Keller, Brian
    Lechtman, Eli
    Bendayan, Reina
    Reilly, Raymond M.
    [J]. MOLECULAR PHARMACEUTICS, 2010, 7 (06) : 2194 - 2206
  • [9] Mucins in ovarian cancer diagnosis and therapy
    Chauhan, Subhash C.
    Kumar, Deepak
    Jaggi, Meena
    [J]. JOURNAL OF OVARIAN RESEARCH, 2009, 2 (01):
  • [10] Quantitative Investigation of Compartmentalized Dynamics of ErbB2 Targeting Gold Nanorods in Live Cells by Single Molecule Spectroscopy
    Chen, Jiji
    Irudayaraj, Joseph
    [J]. ACS NANO, 2009, 3 (12) : 4071 - 4079