Liver transplantation in cystic fibrosis: Monitoring and followup - Personal experience

被引：0

作者：

Alfani, D

Rossi, M

Venettoni, S

Antonelli, M

Quattrucci, S

Della Rocca, G

Antonini, M

Lubrano, R

Castello, M

Cortesini, R

机构：

[1] Univ Rome La Sapienza, Ist Clin Chirurg 2, I-00161 Rome, Italy

[2] Univ Rome La Sapienza, Ist Clin Pediat, I-00161 Rome, Italy

来源：

RIVISTA ITALIANA DI PEDIATRIA-ITALIAN JOURNAL OF PEDIATRICS | 1998年 / 24卷 / 02期

关键词：

liver transplantation; cystic fibrosis; follow-up;

D O I：

暂无

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

About 5-15% of children with cystic fibrosis develop hepatic cirrhosis and progressive portal hypertension. When the portal hypertension worsens these children are likely to develop serious variceal bleeding and other complications including malnutrition and a decline in respiratory function. Isolated liver transplantation is the therapy of choice in patients with cystic fibrosis affected by liver cirrhosis and initial clinical manifestations of portal hypertension in presence of a well preserved pulmonary function (REV1 > 40%). Although the optimal time for liver transplantation is difficult to judge this procedure provides a progressive improvement of patient respiratory function, nutritional status and quality of life, meanwhile not increasing the risk of lung infection due to immunosuppression.

引用

页码：32 / 33

页数：2