Epithelial Sensing of Fungal Invasion

被引：11

作者：

Netea, Mihai G. ^{[1
,2
]}

Kullberg, Bart Jan ^{[1
,2
]}

机构：

[1] Radboud Univ Nijmegen, Dept Med, Med Ctr, NL-6500 HB Nijmegen, Netherlands

[2] Nijmegen Inst Infect Inflammat & Immun N4i, NL-6500 HB Nijmegen, Netherlands

来源：

CELL HOST & MICROBE | 2010年 / 8卷 / 03期

关键词：

CANDIDA-ALBICANS; COLONIZATION; RECOGNITION;

D O I：

10.1016/j.chom.2010.08.008

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The mechanisms discriminating mucosal colonization from invasion by Candida albicans are unclear. In this issue, Moyes et al. show that epithelial cells discriminate between colonizing yeasts and invading hyphae by mechanisms involving c-Fos and MKP1 phosphatase, opening up new avenues for understanding the pathophysiology of mucosal fungal infections.

引用

页码：219 / 220

页数：2

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