Synthesis and Properties of Novel Silver-Containing DNA Molecules

被引：38

作者：

Eidelshtein, Gennady ^{[1
,2
]}

Fardian-Melamed, Natalie ^{[3
,4
]}

Gutkin, Vitaly ^{[4
]}

Basmanov, Dmitry ^{[5
]}

Klinov, Dmitry ^{[5
,6
]}

Rotem, Dvir ^{[3
,4
]}

Levi-Kalisman, Yael ^{[4
,7
]}

Porath, Danny ^{[3
,4
]}

Kotlyar, Alexander ^{[1
,2
]}

机构：

[1] Tel Aviv Univ, Dept Biochem & Mol Biol, George S Wise Fac Life Sci, IL-69978 Tel Aviv, Israel

[2] Tel Aviv Univ, Ctr Nanosci & Nanotechnol, IL-69978 Tel Aviv, Israel

[3] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel

[4] Hebrew Univ Jerusalem, Ctr Nanosci & Nanotechnol, IL-91904 Jerusalem, Israel

[5] Inst Phys Chem Med, Malaya Pirogovskaya Str 1a, Moscow 119435, Russia

[6] State Univ, Russia & Moscow Inst Phys & Technol, 9 Inst Per, Dolgoprudnyi 141700, Moscow Region, Russia

[7] Hebrew Univ Jerusalem, Inst Life Sci, IL-91904 Jerusalem, Israel

来源：

ADVANCED MATERIALS | 2016年 / 28卷 / 24期

基金：

以色列科学基金会; 俄罗斯科学基金会;

关键词：

DEOXYRIBONUCLEIC-ACID; ELECTRICAL-TRANSPORT; CIRCULAR-DICHROISM; CHARGE-TRANSPORT; ION; POLY(DG)-POLY(DC); SURFACE; BASES;

D O I：

10.1002/adma.201505049

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Migration of silver atoms from silver nanoparticles selectively to a double-stranded poly(dG)-poly(dC) polymer leads to metalization of the DNA. As a result the DNA molecules become shorter and thicker (higher), as evident from the atomic force microscopy imaging analysis. The metalized molecules can be detected by transmission and scanning electron microscopy in contrast to the initial non-metalized ones.

引用

页码：4839 / 4844

页数：6

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