Impact of Pirin Protein Expression Level on NF-κB Signaling Pathway Activation

被引：0

作者：

Brzoska, Kamil ^{[1
]}

Kruszewski, Marcin ^{[1
]}

机构：

[1] Inst Nucl Chem & Technol, Ctr Radiobiol & Biol Dosimetry, PL-03195 Warsaw, Poland

来源：

NUCLEAR PHYSICS METHODS AND ACCELERATORS IN BIOLOGY AND MEDICINE | 2009年 / 1204卷

关键词：

NF-kappa B signaling pathway; pirin protein;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

NF-kappa B is a pleoiotropic transcription factor that controls the expression of a large number of genes involved in apoptosis, differentiation, cell growth and immune response. Alterations in NF-kappa B activity are associated with many diseases including cancer. In this work we show that NF-kappa B activation can be modulated by expression of nuclear protein pirin which might affect the effectiveness of anticancer therapies.

引用

页码：260 / 261

页数：2

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