The GWAS Diversity Monitor tracks diversity by disease in real time

被引:213
作者
Mills, Melinda C. [1 ,2 ]
Rahal, Charles [1 ,2 ]
机构
[1] Univ Oxford, Leverhulme Ctr Demog Sci, Oxford, England
[2] Univ Oxford, Nuffield Coll, Oxford, England
基金
欧洲研究理事会; 英国经济与社会研究理事会;
关键词
D O I
10.1038/s41588-020-0580-y
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:242 / 243
页数:2
相关论文
共 11 条
[1]   The population genetics of human disease: The case of recessive, lethal mutations [J].
Amorim, Carlos Eduardo G. ;
Gao, Ziyue ;
Baker, Zachary ;
Diesel, Jose Francisco ;
Simons, Yuval B. ;
Haque, Imran S. ;
Pickrell, Joseph ;
Przeworski, Molly .
PLOS GENETICS, 2017, 13 (09)
[2]   The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019 [J].
Buniello, Annalisa ;
MacArthur, Jacqueline A. L. ;
Cerezo, Maria ;
Harris, Laura W. ;
Hayhurst, James ;
Malangone, Cinzia ;
McMahon, Aoife ;
Morales, Joannella ;
Mountjoy, Edward ;
Sollis, Elliot ;
Suveges, Daniel ;
Vrousgou, Olga ;
Whetzel, Patricia L. ;
Amode, Ridwan ;
Guillen, Jose A. ;
Riat, Harpreet S. ;
Trevanion, Stephen J. ;
Hall, Peggy ;
Junkins, Heather ;
Flicek, Paul ;
Burdett, Tony ;
Hindorff, Lucia A. ;
Cunningham, Fiona ;
Parkinson, Helen .
NUCLEIC ACIDS RESEARCH, 2019, 47 (D1) :D1005-D1012
[3]   Analysis of polygenic risk score usage and performance in diverse human populations [J].
Duncan, L. ;
Shen, H. ;
Gelaye, B. ;
Meijsen, J. ;
Ressler, K. ;
Feldman, M. ;
Peterson, R. ;
Domingue, B. .
NATURE COMMUNICATIONS, 2019, 10 (1)
[4]   Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans [J].
Genovese, Giulio ;
Friedman, David J. ;
Ross, Michael D. ;
Lecordier, Laurence ;
Uzureau, Pierrick ;
Freedman, Barry I. ;
Bowden, Donald W. ;
Langefeld, Carl D. ;
Oleksyk, Taras K. ;
Knob, Andrea L. Uscinski ;
Bernhardy, Andrea J. ;
Hicks, Pamela J. ;
Nelson, George W. ;
Vanhollebeke, Benoit ;
Winkler, Cheryl A. ;
Kopp, Jeffrey B. ;
Pays, Etienne ;
Pollak, Martin R. .
SCIENCE, 2010, 329 (5993) :841-845
[5]   Clinical use of current polygenic risk scores may exacerbate health disparities [J].
Martin, Alicia R. ;
Kanai, Masahiro ;
Kamatani, Yoichiro ;
Okada, Yukinori ;
Neale, Benjamin M. ;
Daly, Mark J. .
NATURE GENETICS, 2019, 51 (04) :584-591
[6]   Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations [J].
Martin, Alicia R. ;
Gignoux, Christopher R. ;
Walters, Raymond K. ;
Wojcik, Genevieve L. ;
Neale, Benjamin M. ;
Gravel, Simon ;
Daly, Mark J. ;
Bustamante, Carlos D. ;
Kenny, Eimear E. .
AMERICAN JOURNAL OF HUMAN GENETICS, 2017, 100 (04) :635-649
[7]   A scientometric review of genome-wide association studies [J].
Mills, Melinda C. ;
Rahal, Charles .
COMMUNICATIONS BIOLOGY, 2019, 2 (1)
[8]  
Mostafavi H., 2019, PREPRINT BIORXIV, DOI [10.1101/629949, DOI 10.1101/629949]
[9]  
Sirugo G, 2019, CELL, V177, P26, DOI [10.1016/j.cell.2019.02.048, 10.1016/j.cell.2019.04.032]
[10]   The personal and clinical utility of polygenic risk scores [J].
Torkamani, Ali ;
Wineinger, Nathan E. ;
Topol, Eric J. .
NATURE REVIEWS GENETICS, 2018, 19 (09) :581-590