DLC1 and Liver Cancer: The Akt Connection

被引:3
|
作者
Wuestefeld, Torsten
Zender, Lars [1 ]
机构
[1] Helmholtz Ctr Infect Res, D-38124 Braunschweig, Germany
关键词
HUMAN HEPATOCELLULAR-CARCINOMA; GTPASE-ACTIVATING PROTEIN; SUPPRESSOR GENE DLC1; TUMOR-SUPPRESSOR; ABERRANT METHYLATION; PROSTATE-CANCER; CELL; 8P22; EXPRESSION; PROGNOSIS;
D O I
10.1053/j.gastro.2010.08.016
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:1093 / 1096
页数:5
相关论文
共 50 条
  • [31] The Role of Dlc1 Isoform 2 in K-Ras2G12D Induced Thymic Cancer
    Sabbir, Mohammad Golam
    Prieditis, Heather
    Ravinsky, Esther
    Mowat, Michael R. A.
    PLOS ONE, 2012, 7 (07):
  • [32] Tensin1 positively regulates RhoA activity through its interaction with DLC1
    Shih, Yi-Ping
    Sun, Peng
    Wang, Aifeng
    Lo, Su Hao
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 1853 (12): : 3258 - 3265
  • [33] DLC1 induces expression of E-cadherin in prostate cancer cells through Rho pathway and suppresses invasion
    Tripathi, V.
    Popescu, N. C.
    Zimonjic, D. B.
    ONCOGENE, 2014, 33 (06) : 724 - 733
  • [34] Curcumin inhibits growth of human breast cancer cells through demethylation of DLC1 promoter
    Liu, Yufei
    Zhou, Jun
    Hu, Yuchang
    Wang, Junjie
    Yuan, Chengfu
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2017, 425 (1-2) : 47 - 58
  • [35] Significance of genetic variants in DLC1 and their association with hepatocellular carcinoma
    Xie, Cheng-Rong
    Sun, Hong-Guang
    Sun, Yu
    Zhao, Wen-Xiu
    Zhang, Sheng
    Wang, Xiao-Min
    Yin, Zhen-Yu
    MOLECULAR MEDICINE REPORTS, 2015, 12 (03) : 4203 - 4209
  • [36] Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer
    Park, Hansoo
    Cho, Sung-Yup
    Kim, Hyerim
    Na, Deukchae
    Han, Jee Yun
    Chae, Jeesoo
    Park, Changho
    Park, Ok-Kyoung
    Min, Seoyeon
    Kang, Jinjoo
    Choi, Boram
    Min, Jimin
    Kwon, Jee Young
    Suh, Yun-Suhk
    Kong, Seong-Ho
    Lee, Hyuk-Joon
    Liu, Edison T.
    Kim, Jong-Il
    Kim, Sunghoon
    Yang, Han-Kwang
    Lee, Charles
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (40) : 12492 - 12497
  • [37] Silencing of DLC1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells
    Shih, Yi-Ping
    Takada, Yoshikazu
    Lo, Su Hao
    MOLECULAR CANCER RESEARCH, 2012, 10 (01) : 34 - 39
  • [38] DLC1 suppresses NF-κB activity in prostate cancer cells due to its stabilizing effect on adherens junctions
    Tripathi, Veenu
    Popescu, Nicholas C.
    Zimonjic, Drazen B.
    SPRINGERPLUS, 2014, 3 : 1 - 12
  • [39] Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas
    M. Bujko
    P. Kober
    N. Rusetska
    M. Wakuła
    K. Goryca
    E. Grecka
    E. Matyja
    J. Neska
    T. Mandat
    W. Bonicki
    J. A. Siedlecki
    Journal of Neuro-Oncology, 2016, 130 : 473 - 484
  • [40] DLC1 Interaction with S100A10 Mediates Inhibition of In Vitro Cell Invasion and Tumorigenicity of Lung Cancer Cells through a RhoGAP-Independent Mechanism
    Yang, Xuyu
    Popescu, Nicholas C.
    Zimonjic, Drazen B.
    CANCER RESEARCH, 2011, 71 (08) : 2916 - 2925