Guillain-Barre syndrome in children: subtypes and outcome

被引:14
作者
Karalok, Zeynep Selen [1 ]
Taskin, Birce Dilge [1 ]
Yanginlar, Zeliha Brohi [1 ]
Gurkas, Esra [1 ]
Guven, Alev [1 ]
Degerliyurt, Aydan [1 ]
Unlu, Ece [2 ]
Kose, Gulsen [3 ]
机构
[1] Ankara Childrens Hematol Oncol Training & Res Hos, Dept Pediat Neurol, TR-06110 Ankara, Turkey
[2] Minist Hlth, Diskapi Yildirim Beyazit Educ & Res Hosp, Dept Phys Med & Rehabil, Ankara, Turkey
[3] Sisli Hamidiye Etfal Res & Training Hosp, Dept Pediat Neurol, Istanbul, Turkey
关键词
Childhood GBS; Early treatment; Outcome; Subtypes; MOTOR AXONAL NEUROPATHY; AUTONOMIC DYSFUNCTION; PROGNOSIS; RECOVERY; PATTERNS; POLYNEUROPATHY; MULTICENTER; ANTIBODIES; INFECTION; VARIANTS;
D O I
10.1007/s00381-018-3856-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective This study reviews the clinical features, subtypes, and outcomes of childhood Guillain-Barre syndrome (GBS). Methods Fifty-four children who attended a tertiary care training and research hospital in Turkey were enrolled in the study. Results The mean age was 6.5 +/- 4.2 years and 32 patients (59.5%) were male. The most common subtype of GBS was acute inflammatory demyelinating polyneuropathy (AIDP), which was seen in 27 patients (50%). Having antecedent history, especially upper respiratory tract infection was significantly more common in AIDP (P = 0.028). Sensorial symptoms were significantly more frequent in axonal type GBS (P = 0.001). When we compare the demyelinating and axonal forms, all of the groups had favorable outcome. Conclusion The diagnosis of pediatric GBS can be delayed because of its variable presentation. Early admission to hospital and early treatment are important for decreasing the need for respiratory support and improving the outcome.
引用
收藏
页码:2291 / 2297
页数:7
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