Successful management of adult respiratory distress syndrome (ARDS) after high-dose chemotherapy and peripheral blood progenitor cell rescue by non-invasive ventilatory support

被引:19
作者
Rabitsch, W
Staudinger, T
Brugger, SA
Reiter, E
Keil, F
Herold, C
Lechner, K
Greinix, HT
Kalhs, P
机构
[1] Univ Vienna, Dept Internal Med 1, Bone Marrow Transplantat Unit, A-1090 Vienna, Austria
[2] Univ Vienna, Dept Internal Med 1, Intens Care Unit, A-1090 Vienna, Austria
[3] Univ Vienna, Dept Radiol, A-1090 Vienna, Austria
[4] Univ Vienna, Dept Internal Med 1, Hematol Unit, A-1090 Vienna, Austria
关键词
high-dose chemotherapy and peripheral blood progenitor cell rescue non-invasive ventilatory support; non-invasive ventilation; CPAP; ARDS;
D O I
10.1038/sj.bmt.1701215
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A 34-year-old man suffering from Hodgkin's disease underwent high-dose chemotherapy (CBV) followed by transplantation of autologous peripheral blood stem cells. On day +6 after peripheral blood stem cell transplant (PBSCT) bacterial pneumonia developed. Along with rapid engraftment during stimulation with G-CSF adult respiratory distress syndrome (ARDS) developed within 4 days, High-flow CPAP (continuous positive airway pressure) ventilation via a sealed face-mask was initiated. The patient tolerated the sealed face-mask very well, and CPAP was continuously administered for 4 days, thus avoiding intubation, High-flow CPAP may offer a therapeutic alternative in selected patients with respiratory compromise after PBSCT.
引用
收藏
页码:1067 / 1069
页数:3
相关论文
共 12 条
[1]   OUTCOME OF RECIPIENTS OF BONE-MARROW TRANSPLANTS WHO REQUIRE INTENSIVE-CARE UNIT SUPPORT [J].
AFESSA, B ;
TEFFERI, A ;
HOAGLAND, HC ;
LETENDRE, L ;
PETERS, SG .
MAYO CLINIC PROCEEDINGS, 1992, 67 (02) :117-122
[2]  
Branson R D, 1985, Respir Care, V30, P846
[3]  
FABERLANGENDOEN K, 1993, BONE MARROW TRANSPL, V12, P501
[4]   CONTINUOUS POSITIVE AIRWAY PRESSURE WITHOUT TRACHEAL INTUBATION IN SPONTANEOUSLY BREATHING PATIENTS [J].
GREENBAUM, DM ;
MILLEN, JE ;
EROSS, B ;
SNYDER, JV ;
GRENVIK, A ;
SAFAR, P .
CHEST, 1976, 69 (05) :615-620
[5]   PULMONARY COMPLICATIONS OF BONE-MARROW TRANSPLANTATION [J].
KROWKA, MJ ;
ROSENOW, EC ;
HOAGLAND, HC .
CHEST, 1985, 87 (02) :237-246
[6]  
LEGER P, 1988, American Review of Respiratory Disease, V137, P63
[7]  
OQUIN T, 1988, SEMIN ONCOL NURSING, V14, P115
[8]  
PATRICK W, 1993, AM REV RESPIR DIS, V147, pA984
[9]   OUTCOME OF PATIENTS REQUIRING MEDICAL ICU ADMISSION FOLLOWING BONE-MARROW TRANSPLANTATION [J].
PAZ, HL ;
CRILLEY, P ;
WEINAR, M ;
BRODSKY, I .
CHEST, 1993, 104 (02) :527-531
[10]   TREATMENT OF THE ADULT RESPIRATORY-DISTRESS SYNDROME WITH CONTINUOUS POSITIVE AIRWAY PRESSURE [J].
VENUS, B ;
JACOBS, HK ;
LIM, L .
CHEST, 1979, 76 (03) :257-261