Prognostic Value of Serum Creatinine Levels in Patients with Epithelial Ovarian Cancer

被引：21
|
作者：
Lafleur, Judith [1 ,3 ]
Hefler-Frischmuth, Katrin [2 ]
Grimm, Christoph [4 ]
Schwameis, Richard [1 ,4 ]
Gensthaler, Lisa [4 ]
Reiser, Elisabeth [4 ]
Hefler, Lukas A. [1 ,3 ]
机构：
[1] Ordensklinikum Linz, Dept Gynecol, Seilerstatte 4, A-4020 Linz, Austria
[2] Ordensklinikum Linz, Dept Internal Med 1, Linz, Austria
[3] Karl Landsteiner Inst Gynecol Surg & Oncol, Linz, Austria
[4] Med Univ Vienna, Comprehens Canc Ctr, Dept Gen Gynecol & Gynecol Oncol, Gynecol Canc Unit, Vienna, Austria
来源：
ANTICANCER RESEARCH | 2018年 / 38卷 / 09期
关键词：
Ovarian cancer; creatinine; prognosis; ALBUMIN;
D O I：
10.21873/anticanres.12834
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Aim: To evaluate preoperative serum creatinine level as a prognostic parameter in patients with primary epithelial ovarian cancer (EOC). Patients and Methods: In a retrospective cohort study, serum levels of creatinine were evaluated in 498 patients with EOC. Data were extracted from our prospectively maintained database. Results were correlated with clinicopathological parameters and patient survival. Results: The mean pre-therapeutic serum creatinine level in patients with EOC was 0.84 +/- 0.40 mg/dI. A serum creatinine level of 1.2 mg/dl or higher was found in 22 (4.4%) patients and associated with poor survival. In a multivariate logistic regression analysis, the serum creatinine level was a significant independent prognostic parameter of overall survival. Conclusion: The preoperative serum level of creatinine may be useful as an additional independent prognostic parameter in patients with EOC.
引用
收藏
页码：5127 / 5130
页数：4
相关论文
共 50 条
  • [21] The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer
    de Graeff, P.
    Crijns, A. P. G.
    ten Hoor, K. A.
    Klip, H. G.
    Hollema, H.
    Oien, K.
    Bartlett, J. M.
    Wisman, G. B. A.
    de Bock, G. H.
    de Vries, E. G. E.
    de Jong, S.
    van der Zee, A. G. J.
    BRITISH JOURNAL OF CANCER, 2008, 99 (02) : 341 - 349
  • [22] Prognostic value of BRCA1 promoter methylation for patients with epithelial ovarian cancer
    Azais, Henri
    Garinet, Simon
    Benoit, Louise
    de Jesus, Julie
    Zizi, Mohamed
    Landman, Samuel
    Bats, Anne-Sophie
    Taly, Valerie
    Laurent-Puig, Pierre
    Blons, Helene
    JOURNAL OF GYNECOLOGY OBSTETRICS AND HUMAN REPRODUCTION, 2024, 53 (07)
  • [23] The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer
    P de Graeff
    A P G Crijns
    K A ten Hoor
    H G Klip
    H Hollema
    K Oien
    J M Bartlett
    G B A Wisman
    G H de Bock
    E G E de Vries
    S de Jong
    A G J van der Zee
    British Journal of Cancer, 2008, 99 : 341 - 349
  • [24] Prognostic Value of ADAMTS Proteases and Their Substrates in Epithelial Ovarian Cancer
    Lima, Maira Assis
    dos Santos, Liliane
    Turri, Jose Antonio
    Nonogaki, Suely
    Buim, Marcilei
    Lima, Joema Felipe
    Viana Pinheiro, Joao de Jesus
    Bueno de Toledo Osorio, Cynthia Aparecida
    Soares, Fernando Augusto
    Freitas, Vanessa Morals
    PATHOBIOLOGY, 2016, 83 (06) : 316 - 326
  • [25] Prognostic value of Ki-67 in patients with ovarian cancer
    Wan, Su
    Su, Chang
    Wang, Yong
    Ding, Jin
    Jiang, Qingya
    Ding, Huafeng
    Ni, Guantai
    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2025, 46 (01) : 76 - 81
  • [26] Serum tetranectin is a significant prognostic marker in ovarian cancer patients
    Begum, Farah Diba
    Hogdall, Estrid
    Christensen, Ib Jarle
    Kjaer, Susanne Kruger
    Blaakaer, Jan
    Christensen, Lise
    Hogdall, Claus
    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2010, 89 (02) : 190 - 198
  • [27] Prognostic value of HE4 in patients with ovarian cancer
    Yuan, Cunzhong
    Li, Rongrong
    Yan, Shi
    Kong, Beihua
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2018, 56 (07) : 1026 - 1034
  • [28] Prognostic value of serum levels of soluble MICA (sMICA) in patients with prostate cancer
    Liu, Y.
    Guo, X.
    Xing, M.
    Zhao, K.
    Luo, L.
    Du, J.
    BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 2018, 75 (02) : 98 - 100
  • [29] Variation and prognostic value of serum plasminogen activator inhibitor-1 before and after chemotherapy in patients with epithelial ovarian cancer
    Chen, Shutong
    Tai, Haifeng
    Tong, Xiaowen
    Wang, Jianjun
    Yang, Fang
    Yang, Yang
    Ouyang Yiqin
    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2014, 40 (09) : 2058 - 2065
  • [30] Prognostic Value of Elevated Pre-treatment Serum CA-125 in Epithelial Ovarian Cancer: A Meta-Analysis
    Wang, Qingyi
    Feng, Xiaoling
    Liu, Xiaofang
    Zhu, Siyu
    FRONTIERS IN ONCOLOGY, 2022, 12
12345