Advances in capture methods of circulating tumor cells

被引:1
作者
Liu Lukuan [1 ,2 ,3 ]
Yang Kaiguang [1 ]
Liang Zhen [1 ]
Zhang Lihua [1 ]
Zhang Yukui [1 ]
机构
[1] Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
关键词
circulating tumor cells (CTCs); selective capture; biophysics; affinity; artificial antibody; review; HIGHLY EFFICIENT CAPTURE; CANCER-PATIENTS; BREAST-CANCER; IN-VIVO; MULTIPLE TYPES; LABEL-FREE; RELEASE; BLOOD; SEPARATION; HYDROGEL;
D O I
10.3724/SP.J.1123.2018.12016
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Since circulating tumor cells (CTCs) in the blood carry the genetic and phenotypic information of tumor tissues, they are regarded as important markers for liquid biopsy, especially for the early diagnosis of cancer, determination of treatment options and evaluation of prognosis. However, the capture and detection of CTCs is challenging because of their extremely low concentration in blood. In this review, recent advances in capture methods of CTCs based on their biophysical properties, affinity, and artificial antibodies are summarized. The advantages and drawbacks of these methods are discussed from the aspects of capture efficiency, capture purity and maintenance of activity after release. Future trends in CTCs capture are also discussed.
引用
收藏
页码:358 / 366
页数:9
相关论文
共 64 条
[1]   OPINION Challenges in circulating tumour cell research [J].
Alix-Panabieres, Catherine ;
Pantel, Klaus .
NATURE REVIEWS CANCER, 2014, 14 (09) :623-631
[2]   Comparison of assay methods for detection of circulating tumor cells in metastatic breast cancer: AdnaGen AdnaTest BreastCancer Select/Detect™ versus Veridex CellSearch™ system [J].
Andreopoulou, E. ;
Yang, L. -Y. ;
Rangel, K. M. ;
Reuben, J. M. ;
Hsu, L. ;
Krishnamurthy, S. ;
Valero, V. ;
Fritsche, H. A. ;
Cristofanilli, M. .
INTERNATIONAL JOURNAL OF CANCER, 2012, 130 (07) :1590-1597
[3]   From nano to micro: topographical scale and its impact on cell adhesion, morphology and contact guidance [J].
Anh Tuan Nguyen ;
Sathe, Sharvari R. ;
Yim, Evelyn K. F. .
JOURNAL OF PHYSICS-CONDENSED MATTER, 2016, 28 (18)
[4]   Peptide-based isolation of circulating tumor cells by magnetic nanoparticles [J].
Bai, Linling ;
Du, Yimeng ;
Peng, Jiaxi ;
Liu, Yi ;
Wang, Yanmei ;
Yang, Yanlian ;
Wang, Chen .
JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2 (26) :4080-4088
[5]  
Bao JJ, 2017, CHIN J CHROMATOGR, V35, P129, DOI 10.3724/SP.J.1123.2016.09005
[6]   SEPARATION OF HUMAN BREAST-CANCER CELLS FROM BLOOD BY DIFFERENTIAL DIELECTRIC AFFINITY [J].
BECKER, FF ;
WANG, XB ;
HUANG, Y ;
PETHIG, R ;
VYKOUKAL, J ;
GASCOYNE, PRC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (03) :860-864
[7]   Engineering Substrate Topography at the Micro- and Nanoscale to Control Cell Function [J].
Bettinger, Christopher J. ;
Langer, Robert ;
Borenstein, Jeffrey T. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (30) :5406-5415
[8]   Advanced Materials for the Recognition and Capture of Whole Cells and Microorganisms [J].
Bole, Amanda L. ;
Manesiotis, Panagiotis .
ADVANCED MATERIALS, 2016, 28 (27) :5349-5366
[9]   High-Efficiency Capture of Individual and Cluster of Circulating Tumor Cells by a Microchip Embedded with Three-Dimensional Poly(dimethylsiloxane) Scaffold [J].
Cheng, Shi-Bo ;
Xie, Min ;
Xu, Jia-Quan ;
Wang, Jing ;
Lv, Song-Wei ;
Guo, Shan ;
Shu, Ying ;
Wang, Ming ;
Dong, Wei-Guo ;
Huang, Wei-Hua .
ANALYTICAL CHEMISTRY, 2016, 88 (13) :6773-6780
[10]   Inertial microfluidics [J].
Di Carlo, Dino .
LAB ON A CHIP, 2009, 9 (21) :3038-3046