Mechanism of basic calcium phosphate crystal-induced Upregulation of matrix metalloproteinase-13 in human osteoarthritic synovial fibroblasts:: Effect of prostaglandin E2+

被引：0
|
作者：
Molloy, ES
Morgan, MP
Doherty, GA
O'Byrne, J
Fitzgerald, DJ
McCarthy, GM
机构：
[1] Royal Coll Surgeons Ireland, Dublin 2, Ireland
[2] Univ Coll Dublin, Conway Inst, Dublin 2, Ireland
[3] Mater Misericordiae Univ Hosp, Dept Orthopaed Surg, Dublin 7, Ireland
来源：
ARTHRITIS AND RHEUMATISM | 2005年 / 52卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：S101 / S101
页数：1
相关论文
共 25 条
  • [1] Mechanism of basic calcium phosphate crystal-stimulated matrix metalloproteinase-13 expression by osteoarthritic synovial fibroblasts: inhibition by prostaglandin E2
    Molloy, E. S.
    Morgan, M. P.
    Doherty, G. A.
    McDonnell, B.
    O'Byrne, J.
    Fitzgerald, D. J.
    McCarthy, G. M.
    ANNALS OF THE RHEUMATIC DISEASES, 2008, 67 (12) : 1773 - 1779
  • [2] The EP4 receptor mediates a positive feedback mechanism on basic calcium phosphate crystal-induced prostaglandin E2, production in human osteoarthritic synovial fibroblasts.
    Molloy, ES
    Doherty, G
    Morgan, M
    O'Byrne, J
    Fitzgerald, D
    Crofford, LJ
    McCarthy, GM
    ARTHRITIS AND RHEUMATISM, 2004, 50 (09): : S62 - S63
  • [3] Basic calcium phosphate crystals activate human osteoarthritic synovial fibroblasts and induce matrix metalloproteinase-13 (collagenase-3) in adult porcine articular chondrocytes
    McCarthy, GM
    Westfall, PR
    Masuda, I
    Christopherson, PA
    Cheung, HS
    Mitchell, PG
    ANNALS OF THE RHEUMATIC DISEASES, 2001, 60 (04) : 399 - 406
  • [4] Basic calcium phosphate crystal-induced prostaglandin E2 production in human fibroblasts -: Role of cyclooxygenase 1, cyclooxygenase 2, and interleukin-1β
    Morgan, MP
    Whelan, LC
    Sallis, JD
    McCarthy, CJ
    Fitzgerald, DJ
    McCarthy, GM
    ARTHRITIS AND RHEUMATISM, 2004, 50 (05): : 1642 - 1649
  • [5] MISOPROSTOL, A PROSTAGLANDIN-E1 ANALOG, INHIBITS BASIC CALCIUM-PHOSPHATE CRYSTAL-INDUCED MITOGENESIS AND COLLAGENASE ACCUMULATION IN HUMAN FIBROBLASTS
    MCCARTHY, GM
    MITCHELL, PG
    CHEUNG, HS
    CALCIFIED TISSUE INTERNATIONAL, 1993, 52 (06) : 434 - 437
  • [6] Basic calcium phosphate crystal-induced Egr-1 expression stimulates mitogenesis in human fibroblasts
    Zeng, XR
    Sun, YB
    Wenger, L
    Cheung, HS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 330 (03) : 658 - 664
  • [7] Mechanism of basic calcium phosphate crystal-stimulated cyclo-oxygenase-1 up-regulation in osteoarthritic synovial fibroblasts
    Molloy, E. S.
    Morgan, M. P.
    Doherty, G. A.
    McDonnell, B.
    Hilliard, M.
    O'Byrne, J.
    Fitzgerald, D. J.
    McCarthy, G. M.
    RHEUMATOLOGY, 2008, 47 (07) : 965 - 971
  • [8] Induction of matrix metalloproteinase-8 in human fibroblasts by basic calcium phosphate and calcium pyrophosphate dihydrate crystals: Effect of phosphocitrate
    Reuben, PM
    Wenger, L
    Cruz, M
    Cheung, HS
    CONNECTIVE TISSUE RESEARCH, 2001, 42 (01) : 1 - +
  • [9] Phosphocitrate augments basic calcium phosphate crystal-induced NO production but inhibits the suppressive effects of BCP crystals on caspase-3 activation in human synovial fibroblasts.
    Whelan, LC
    Misstear, K
    Sallis, JD
    O'Byrne, JM
    McCarthy, GM
    ARTHRITIS AND RHEUMATISM, 2004, 50 (09): : S62 - S62
  • [10] Molecular mechanism of basic calcium phosphate crystal-induced activation of human fibroblasts -: Role of nuclear factor κB, activator protein 1, and protein kinase C
    McCarthy, GM
    Augustine, JA
    Baldwin, AS
    Christopherson, PA
    Cheung, HS
    Westfall, PR
    Scheinman, RI
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (52) : 35161 - 35169
123