Properties of xyloglucan hydrogel as the biomedical sustained-release carriers

被引：28

作者：

Chen, Didi ^{[1
]}

Guo, Pei ^{[1
]}

Chen, Sha ^{[1
]}

Cao, Yu ^{[1
,2
]}

Ji, Wanzhen ^{[1
]}

Lei, Xia ^{[1
]}

Liu, Lina ^{[1
]}

Zhao, Peiguang ^{[1
]}

Wang, Ruihong ^{[1
]}

Qi, Chao ^{[2
]}

Liu, Yanli ^{[2
]}

He, Hongxuan ^{[3
]}

机构：

[1] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China

[2] Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Coll Life Sci, Wuhan 430079, Peoples R China

[3] Chinese Acad Sci, Natl Res Ctr Wildlife Born Dis, Key Lab Anim Ecol & Conservat Biol, Inst Zool, Beijing 100101, Peoples R China

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 2012年 / 23卷 / 04期

关键词：

IN-VITRO; GELS; DELIVERY;

D O I：

10.1007/s10856-012-4564-z

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This study introduces an easy method of preparing xyloglucan hydrogel from xyloglucan, which is purified from tamarind seed gum. Xyloglucan hydrogel was prepared in 2 wt% solution by treating with beta-galactosidase. Physical and chemical properties (molecular mass, size and viscosity) of xyloglucan hydrogel and xyloglucan solution were tested for a comparison. Experiments of drug release in vitro and in vivo were operated to investigate the potentialities of xyloglucan hydrogel as the biomedical sustained-release carriers for drug delivery system.

引用

页码：955 / 962

页数：8

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