Properties of xyloglucan hydrogel as the biomedical sustained-release carriers

被引:27
|
作者
Chen, Didi [1 ]
Guo, Pei [1 ]
Chen, Sha [1 ]
Cao, Yu [1 ,2 ]
Ji, Wanzhen [1 ]
Lei, Xia [1 ]
Liu, Lina [1 ]
Zhao, Peiguang [1 ]
Wang, Ruihong [1 ]
Qi, Chao [2 ]
Liu, Yanli [2 ]
He, Hongxuan [3 ]
机构
[1] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China
[2] Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Coll Life Sci, Wuhan 430079, Peoples R China
[3] Chinese Acad Sci, Natl Res Ctr Wildlife Born Dis, Key Lab Anim Ecol & Conservat Biol, Inst Zool, Beijing 100101, Peoples R China
关键词
IN-VITRO; GELS; DELIVERY;
D O I
10.1007/s10856-012-4564-z
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This study introduces an easy method of preparing xyloglucan hydrogel from xyloglucan, which is purified from tamarind seed gum. Xyloglucan hydrogel was prepared in 2 wt% solution by treating with beta-galactosidase. Physical and chemical properties (molecular mass, size and viscosity) of xyloglucan hydrogel and xyloglucan solution were tested for a comparison. Experiments of drug release in vitro and in vivo were operated to investigate the potentialities of xyloglucan hydrogel as the biomedical sustained-release carriers for drug delivery system.
引用
收藏
页码:955 / 962
页数:8
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