Synthesis, Spectroscopic Characterization and Antibacterial Activity of some Chloro Dimethylsulphoxide/Tetramethylenesulphoxide Ruthenium (II)/(III) Complexes with 1, 2, 3-Benzotriazole

Synthesis and characterization of seven ruthenium (II) and ruthenium (III) chloro sulphoxide complexes with 1, 2, 3-benzotriazole are reported. Three different formulations exist: [cis, fac-RuCl2(so)(3)(btz)]; [trans-RuCl2(so)(3)(btz)] and [trans-RuCl4(so)(btz)](-)[X](+); where so=dimethylsulphoxide/tetramethylenesulphoxide; btz = 1, 2, 3-benzotriazole and [X](+) = [(btz)H](+) or Na+. These complexes were characterized by elemental analysis, conductivity measurements, magnetic susceptibility, FT-IR, H-1-NMR, C-13{H-1}-NMR and electronic spectroscopy. Complexes were screened for their antibacterial activity and found more potent than 1, 2, 3-benzotriazole ligand and precursor ruthenium compounds against gram-negative bacteria Escherichia coli. All the samples were compared with antibiotic Chloramphenicol for reference.