Study of the Effects of Ionic Liquids on Lipid Bilayers

被引:0
作者
Young, Taylor T. [1 ]
Sarles, Stephen A. [2 ]
Wu, Tianyu [3 ]
Green, Matthew [3 ]
Long, Timothy E. [3 ]
Leo, Donald J. [1 ]
机构
[1] Virginia Tech, Dept Mech Engn, Blacksburg, VA 24061 USA
[2] Univ Tennessee, Dept Mech, Dept Aerosp & Biomed Engn, Knoxville, TN 37996 USA
[3] Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA
来源
BIOINSPIRATION, BIOMIMETICS, AND BIOREPLICATION 2012 | 2012年 / 8339卷
关键词
Ionic Liquid; Droplet Interface Lipid Bilayer; Alamethicin; Regulated Attachment Method;
D O I
10.1117/12.915078
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.
引用
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页数:11
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