Potential tissue selectivity of dietary phytoestrogens and estrogens

被引：60

作者：

Cassidy, A ^{[1
]}

机构：

[1] Univ Surrey, Sch Biol Sci, Ctr Nutr & Food Safety, Guildford GU2 5XH, Surrey, England

来源：

CURRENT OPINION IN LIPIDOLOGY | 1999年 / 10卷 / 01期

关键词：

D O I：

10.1097/00041433-199902000-00009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recent discovery of a second estrogen receptor subtype, estrogen receptor-beta, may significantly advance our understanding of tissue specific effects of estrogenic compounds, both natural and synthetic. Although specific effects mediated by estrogen receptor beta in vivo remain to be elucidated, hypothetically the existence of two estrogen receptor subtypes (differing in both tissue distribution and biological activity) may help to explain the curious pharmacological behaviour of many estrogenic and antiestrogenic compounds, including the naturally occurring dietary phytoestrogens. Curr Opin Lipidol 10:47-52. (C) 1999 Lippincott Williams & Wilkins.

引用

页码：47 / 52

页数：6

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