Potential tissue selectivity of dietary phytoestrogens and estrogens

被引：60
作者：
Cassidy, A [1 ]
机构：
[1] Univ Surrey, Sch Biol Sci, Ctr Nutr & Food Safety, Guildford GU2 5XH, Surrey, England
来源：
CURRENT OPINION IN LIPIDOLOGY | 1999年 / 10卷 / 01期
关键词：
D O I：
10.1097/00041433-199902000-00009
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The recent discovery of a second estrogen receptor subtype, estrogen receptor-beta, may significantly advance our understanding of tissue specific effects of estrogenic compounds, both natural and synthetic. Although specific effects mediated by estrogen receptor beta in vivo remain to be elucidated, hypothetically the existence of two estrogen receptor subtypes (differing in both tissue distribution and biological activity) may help to explain the curious pharmacological behaviour of many estrogenic and antiestrogenic compounds, including the naturally occurring dietary phytoestrogens. Curr Opin Lipidol 10:47-52. (C) 1999 Lippincott Williams & Wilkins.
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页码：47 / 52
页数：6
相关论文
共 51 条
[1]   QUANTITATIVE-DETERMINATION OF LIGNANS AND ISOFLAVONOIDS IN PLASMA OF OMNIVOROUS AND VEGETARIAN WOMEN BY ISOTOPE-DILUTION GAS-CHROMATOGRAPHY MASS-SPECTROMETRY [J].
ADLERCREUTZ, H ;
FOTSIS, T ;
LAMPE, J ;
WAHALA, K ;
MAKELA, T ;
BRUNOW, G ;
HASE, T .
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1993, 53 :5-18
[2]  
Anderson JJB, 1998, P SOC EXP BIOL MED, V217, P345, DOI 10.3181/00379727-217-44243
[3]   METAANALYSIS OF THE EFFECTS OF SOY PROTEIN-INTAKE ON SERUM-LIPIDS [J].
ANDERSON, JW ;
JOHNSTONE, BM ;
COOKNEWELL, ME .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (05) :276-282
[4]   Differential expression of estrogen receptors alpha and beta mRNA during differentiation of human osteoblast SV-HFO cells [J].
Arts, J ;
Kuiper, GGJM ;
Janssen, JMMF ;
Gustafsson, JA ;
Lowik, CWGM ;
Pols, HAP ;
VanLeeuwen, JPTM .
ENDOCRINOLOGY, 1997, 138 (11) :5067-5070
[5]   STEROID-HORMONE RECEPTORS - MANY ACTORS IN SEARCH OF A PLOT [J].
BEATO, M ;
HERRLICH, P ;
SCHUTZ, G .
CELL, 1995, 83 (06) :851-857
[6]  
Bennetts H. W., 1946, AUSTRALIAN VET JOUR, V22, P2, DOI 10.1111/j.1751-0813.1946.tb15473.x
[7]   Molecular basis of agonism and antagonism in the oestrogen receptor [J].
Brzozowski, AM ;
Pike, ACW ;
Dauter, Z ;
Hubbard, RE ;
Bonn, T ;
Engstrom, O ;
Ohman, L ;
Greene, GL ;
Gustafsson, JA ;
Carlquist, M .
NATURE, 1997, 389 (6652) :753-758
[8]   Physiological effects of phyto-oestrogens in relation to cancer and other human health risks [J].
Cassidy, A .
PROCEEDINGS OF THE NUTRITION SOCIETY, 1996, 55 (1B) :399-417
[9]   BIOLOGICAL EFFECTS OF ISOFLAVONES IN YOUNG-WOMEN - IMPORTANCE OF THE CHEMICAL-COMPOSITION OF SOYBEAN PRODUCTS [J].
CASSIDY, A ;
BINGHAM, S ;
SETCHELL, K .
BRITISH JOURNAL OF NUTRITION, 1995, 74 (04) :587-601
[10]   BIOLOGICAL EFFECTS OF A DIET OF SOY PROTEIN-RICH IN ISOFLAVONES ON THE MENSTRUAL-CYCLE OF PREMENOPAUSAL WOMEN [J].
CASSIDY, A ;
BINGHAM, S ;
SETCHELL, KDR .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1994, 60 (03) :333-340
123456