The effect of chromatin remodeling and modification on RNA-polymerase-mediated transcription initiation

被引:0
|
作者
Shidlovskii, YV [1 ]
Nabirochkina, EN
机构
[1] Russian Acad Sci, Inst Gene Biol, Moscow 119334, Russia
[2] Univ Oslo, Med Res Ctr, Moscow 119334, Russia
基金
俄罗斯基础研究基金会;
关键词
D O I
10.1007/s11177-005-0151-4
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
As eukaryotes are characterized by the presence of chromatin (intricately packaged DNA), special mechanisms are required for preparing the DNA template for operation of the transcription machinery. Recently, a close association between the chromatin state and transcription was found and numerous transcription factors modifying the physical and chemical chromatin state were revealed. This review presents a brief description of transcription initiation on the DNA template within chromatin.
引用
收藏
页码:720 / 727
页数:8
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