Photocatalytic reductive radical-radical coupling of N,N′-cyclicazomethine imines with difluorobromo derivatives

被引：34

作者：

Xia, Peng-Ju ^{[1
]}

Ye, Zhi-Peng ^{[1
]}

Song, Dan ^{[1
]}

Ren, Ji-Wei ^{[1
]}

Wu, Han-Wen ^{[1
]}

Xiao, Jun-An ^{[3
]}

Xiang, Hao-Yue ^{[1
]}

Chen, Xiao-Qing ^{[1
,2
]}

Yang, Hua ^{[1
,2
]}

机构：

[1] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China

[2] Cent S Univ, Key Lab Hunan Prov Water Environm & Agr Prod Safe, Changsha 410083, Hunan, Peoples R China

[3] Guangxi Teachers Educ Univ, Coll Chem & Mat Sci, Nanning 530001, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 18期

基金：

中国国家自然科学基金;

关键词：

AZOMETHINE IMINES; ASCORBIC-ACID; CYCLOADDITION; DIFLUOROALKYLATION; ARYLATION; HYDRAZONES; AGENTS;

D O I：

10.1039/c8cc09385g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A visible-light-induced difluoroalkylation of N, N'-cyclicazomethine imine was successfully realized through a novel photoredox radicalradical cross-coupling reaction. This developed protocol exhibits high functional group tolerance and affords a variety of difluorinated 3-pyrazolidinone scaffolds. Extensive mechanistic investigations have been undertaken, well revealing the involvement of a reductive radical-radical coupling pathway.

引用

页码：2712 / 2715

页数：4

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