Oestrogen receptor beta is not present in the pilosebaceous unit of red deer skin during the non-breeding season

被引：3
|
作者：
Thornton, MJ [1 ]
Taylor, AH
Mulligan, K
Al-Azzawi, F
机构：
[1] Univ Bradford, Dept Biomed Sci, Bradford BD7 1DP, W Yorkshire, England
[2] Leicester Royal Infirm, Dept Obstet & Gynaecol, Leicester, Leics, England
来源：
HORMONE RESEARCH | 2000年 / 54卷 / 5-6期
关键词：
oestrogen receptor beta; androgen receptor; skin; hair follicle; sebaceous gland;
D O I：
10.1159/000053268
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Androgens and oestrogens both have roles in skin physiology. Recently a second oestrogen receptor (ERP) has been identified in androgen-dependent tissues. The red deer grows a breeding season, androgen-dependent mane when plasma testosterone rises; this is replaced with small neck hairs during the non-breeding season. In non-breeding season deer skin, ERP was localised to the blood vessels and arrector pili muscle, but in contrast to human skin, not in the pilosebaceous unit or epidermis. The androgen receptor was not expressed. Further studies with breeding season skin may help to elucidate whether serum androgens or androgen receptor expression can modulate the expression of ERP in skin. Copyright (C) 2001 S. Karger AG, Basel.
引用
收藏
页码：259 / 262
页数：4
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