Effects of amide constituents from pepper on adipogenesis in 3T3-L1 cells

被引：27
|
作者：
Zhang, Hailong [1 ]
Matsuda, Hisashi [1 ]
Nakamura, Seikou [1 ]
Yoshikawa, Masayuki [1 ]
机构：
[1] Kyoto Pharmaceut Univ, Yamashina Ku, Kyoto 6078412, Japan
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2008年 / 18卷 / 11期
关键词：
Piper chaba; amide constituents; retrofractamide A; 3T3-L1; cells; adipogenesis; adiponectin;
D O I：
10.1016/j.bmcl.2008.04.052
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Several amide constituents (piperlonguminine and retrofractamides A, B, and C) from the fruit of Piper chaba promoted adipogenesis of 3T3-L1 cells. Among them, retrofractamide A was the most active and significantly increased the amount of adiponectin released into the medium and the uptake of 2-deoxyglucose into the cells. Retrofractamide A also increased mRNA levels of adiponectin, peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2), glucose transporter 4 (GLUT4), and insulin receptor substrate 1 (IRS-1), but did not act as a PPAR gamma agonist different from troglitazone. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3272 / 3277
页数：6
相关论文
共 50 条
  • [21] Effects of Sargassumoligocystum and Padina australis extract on Adipogenesis and Adipolysis in 3T3-L1 Cells
    Jaswir, I.
    Ahmad, H.
    Susanti, D.
    Bakhtiar, M. T.
    Octavianti, F.
    INTERNATIONAL FOOD RESEARCH JOURNAL, 2017, 24 : S395 - S401
  • [22] Effects of multiple novel bisphenol S analogs on adipogenesis in 3T3-L1 cells
    Sun, Zhendong
    Zhang, Shengnan
    Liang, Jiefeng
    Li, Chuanhai
    Yang, Xiaoxi
    Liu, Qian S.
    Zhou, Qunfang
    Shi, Jianbo
    Zhao, Bin
    Jiang, Guibin
    JOURNAL OF HAZARDOUS MATERIALS, 2025, 489
  • [23] Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cells
    Hsu, Chin-Lin
    Lin, Yu-Jyun
    Ho, Chi-Tang
    Yen, Gow-Chin
    FOOD & FUNCTION, 2012, 3 (01) : 49 - 57
  • [24] Glucagon-like peptide 1 regulates adipogenesis in 3T3-L1 preadipocytes
    Yang, Junpeng
    Ren, Jianmin
    Song, Jun
    Liu, Fuqiang
    Wu, Chuanlong
    Wang, Xuping
    Gong, Lei
    Li, Wenjuan
    Xiao, Fang
    Yan, Fei
    Hou, Xinguo
    Chen, Li
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2013, 31 (06) : 1429 - 1435
  • [25] Nonionic Ethoxylated Surfactants Induce Adipogenesis in 3T3-L1 Cells
    Kassotis, Christopher D.
    Kollitz, Erin M.
    Ferguson, Patrick Lee
    Stapleton, Heather M.
    TOXICOLOGICAL SCIENCES, 2018, 162 (01) : 124 - 136
  • [26] Exogenous Sodium Pyruvate Stimulates Adipogenesis of 3T3-L1 Cells
    Hwang, Ji-Sun
    Kim, Song-Yi
    Jung, Eun-Hye
    Kwon, Mi-Youn
    Kim, Kyoung-Hong
    Cho, Hyeongjin
    Han, Inn-Oc
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2016, 117 (01) : 39 - 48
  • [27] Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells
    Soliman, Mohamed Mohamed
    El-Senosi, Yakut Abdel-Fattah
    Salem, Maysara Mahmoud
    Hamid, Omniya Mahmoud Abdel
    Kazuhiro, Kimura
    JOURNAL OF VETERINARY SCIENCE, 2009, 10 (03) : 197 - 201
  • [28] Co-treatment with dexamethasone and octanoate induces adipogenesis in 3T3-L1 cells
    Takenouchi, T
    Takayama, Y
    Takezawa, T
    CELL BIOLOGY INTERNATIONAL, 2004, 28 (03) : 209 - 216
  • [29] Esculetin induces apoptosis and inhibits adipogenesis in 3T3-L1 cells
    Yang, Jeong-Yeh
    Della-Fera, Mary Anne
    Hartzell, Diane L.
    Nelson-Dooley, Cass
    Hausman, Dorothy B.
    Baile, Clifton A.
    OBESITY, 2006, 14 (10) : 1691 - 1699
  • [30] Neuromedin B receptor disruption impairs adipogenesis in mice and 3T3-L1 cells
    Monteiro de Paula, Gabriela Silva
    Wilieman, Marianna
    Silva, Karina Ribeiro
    Baptista, Leandra Santos
    Boudina, Sihem
    de Souza, Luana Lopes
    Bento-Bernardes, Thais
    Asensi, Karma Dutra
    dos Santos Goldenberg, Regina Coeli
    Pazos-Moura, Carmen Cabanelas
    JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2019, 63 (01) : 93 - 102
12345